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Millipore/MABT44 | Anti-ICAM-3 (CD50) Antibody, clone CBR-IC3/1/MABT44/100 µg
Millipore/MABT44 | Anti-ICAM-3 (CD50) Antibody, clone CBR-IC3/1/MABT44/100 µg
市场价：
¥6340.00
美元价：
3804.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | MABT44 |
| Description | Anti-ICAM-3(CD50)Antibody,cloneCBR-IC3/1 |
| AlternateNames |
|
| BackgroundInformation | Intercellularadhesionmolecule3(ICAM-3orCD50)isaleukocytedifferentiationantigen.ICAM-3isthoughttobeimportantintheadhesionofthefirststagesoftheimmuneresponse.ICAM-3mayalsoplayaroleinactivatingTlymphocytes.ICAM-3isfoundinhighlevelsonrestinglymphocytesandisanimportantligandforLFA-1.ICAM-3istyrosinephosphorylatedandisassociatedwithtyrosinekinaseactivityinhumanneutrophils.ICAM-3maybethereceptorglycoproteinthatistheinitialbacterialbindingsiteforinfectiveendocarditisbyoralstreptococci. |
| ProductInformation | |
|---|---|
| Format | Purified |
| Control |
|
| Presentation | PurifiedmousemonoclonalIgG1κinbuffercontaining0.1MTris-Glycine(pH7.4),150mMNaClwith0.05%sodiumazide. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Stablefor1yearat2-8°Cfromdateofreceipt. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | SKW3cells |
| Clone | CBR-IC31 |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Mouse |
| Isotype | IgG1κ |
| SpeciesReactivity |
|
| AntibodyType | MonoclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | Theproteinencodedbythisgeneisamemberoftheintercellularadhesionmolecule(ICAM)family.AllICAMproteinsaretypeItransmembraneglycoproteins,contain2-9immunoglobulin-likeC2-typedomains,andbindtotheleukocyteadhesionLFA-1protein.ThisproteinisconstitutivelyandabundantlyexpressedbyallleucocytesandmaybethemostimportantligandforLFA-1intheinitiationoftheimmuneresponse.Itfunctionsnotonlyasanadhesionmolecule,butalsoasapotentsignallingmolecule.[providedbyRefSeq]. |
| GeneSymbol |
|
| PurificationMethod | ProteinGPurified |
| UniProtNumber | |
| UniProtSummary | FUNCTION:ICAMproteinsareligandsfortheleukocyteadhesionproteinLFA-1(integrinalpha-L/beta-2).ICAM3isalsoaligandforintegrinalpha-D/beta-2. SUBCELLULARLOCATION:Membrane;Single-passtypeImembraneprotein. PTM:Uponstimulationbyaphysiologicstimulibecomesrapidlyandtransientlyphosphorylatedonserineresidues. N-glycosylated;glycansconsistofamixtureoftri-andtetra-antennarycomplex-typechainsandhigh-mannosechains. SEQUENCESIMILARITIES:Belongstotheimmunoglobulinsuperfamily.ICAMfamily. Contains5Ig-likeC2-type(immunoglobulin-like)domains. |
| MolecularWeight | 59kDacalculated |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
|---|
品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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