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Millipore/MAB4211 | Anti-CD34 Class I Antibody, clone B1-3C5/MAB4211/100 µg
Millipore/MAB4211 | Anti-CD34 Class I Antibody, clone B1-3C5/MAB4211/100 µg
市场价：
¥0.00
美元价：
0.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | MAB4211 |
| BrandFamily | Chemicon® |
| TradeName |
|
| Description | Anti-CD34ClassIAntibody,cloneB1-3C5 |
| ProductInformation | |
|---|---|
| Format | Purified |
| Presentation | Theantibodyissuppliedinphosphatebufferedsaline,pH7.4,containing0.2%bovineserumalbuminand0.1%sodiumazide.Thecharacteristicsofeachlotaretestedbyelectrophoresisandflowcytometry. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Forprolongedperiods,storebelow-20°Cinundilutedaliquots.AVOIDREPEATEDFREEZE/THAWCYCLES.Productstablefor6monthswhenstoredasdirected. WARNING:Themonoclonalreagentsolutioncontains0.1%sodiumazideasapreservative.Duetopotentialhazardsarisingfromthebuildupofthismaterialinpipes,spentreagentshouldbedisposedofwithliberalvolumesofwater. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | KG1humanacutemyelogenouscellline. |
| Clone | B1-3C5 |
| Host | Mouse |
| Specificity | ThisantibodybelongstoCD34(assignedbytheThirdInternationalWorkshoponLeukocyteDifferentiationAntigens,Oxford,1987;Hogg&Horton,1987).Itreactswitha120kDglycoproteinfoundonProgenitorcellpopulationsinhumanbonemarrowandfoetalliver(Katzetal.,1985).Thisantigenisnormallyrestrictedtoimmaturehumanhaemopoieticprecursorcells(Peschel&Koller,1989). Cellreactivity(Tindleetal.,1985): Normal:Noreactionwithnormalperipherallymphocytes,granulocytes,monocytes,erythrocytesandplatelets.Reactswith<4% of="" cells="" in="" normal="" bone="" marrow.=""> Clinical:Reaction Acutemyeloidleukemia(AML,M1andM2)positive Nulllymphoblasticleukemia(NullALL)positive Commonacutelymphoblasticleukemia(CALL)positive Myeloblasticandlymphoblasticcrisesofchronic granulocyticleukemia(CGL)positive Chronicmyeloidleukemia(CML)negative Tcellacutelymphoblasticleukemia(TALL)negative Bcellacutelymphoblasticleukemia(BALL)negative Chroniclymphocyticleukemia(CLL)negative Celllines: ReactswithearlymyeloblastlineKG1.Noreactionwithnull,BorTlymphoid,erythroidorlatermyeloidcelllines. |
| Isotype | IgG1 |
| SpeciesReactivity |
|
| AntibodyType | MonoclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | CD34isamonomericcellsurfaceantigenwithamolecularmassofapproximately110kDthatisselectivelyexpressedonhumanhematopoieticprogenitorcells.[suppliedbyOMIM] |
| GeneSymbol |
|
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P28906#PossIBLeadhesionmoleculewitharoleinearlyhematopoiesisbymediatingtheattachmentofstemcellstothebonemarrowextracellularmatrixordirectlytostromalcells.Couldactasascaffoldfortheattachmentoflineagespecificglycans,allowingstemcellstobindtolectinsexpressedbystromalcellsorothermarrowcomponents.Presentscarbohydrateligandstoselectins. SIZE:385aminoacids;40716Da SUBCELLULARLOCATION:Membrane;Single-passtypeImembraneprotein. TISSUESPECIFICITY:Selectivelyexpressedonhematopoieticprogenitorcellsandthesmallvesselendotheliumofavarietyoftissues. DEVELOPMENTALSTAGE:Onearlyhematopoieticprogenitorcells. PTM:Highlyglycosylated.&PhosphorylatedonserineresiduesbyPKC. DISEASE:SwissProt:P28906#AbnormalCD34expressioninleukemogenesis. SIMILARITY:SwissProt:P28906##BelongstotheCD34family. |
| PhysicochemicalInformation |
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| Dimensions |
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| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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