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Millipore/AB1875 | Anti-VEGF Receptor-3 Antibody/AB1875/100 µg
Millipore/AB1875 | Anti-VEGF Receptor-3 Antibody/AB1875/100 µg
市场价：
¥0.00
美元价：
0.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | AB1875 |
| BrandFamily | Chemicon® |
| TradeName |
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| Description | Anti-VEGFReceptor-3Antibody |
| AlternateNames |
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| ProductInformation | |
|---|---|
| Format | Purified |
| Control |
|
| Presentation | Protein-ApurifiedIgGfractioninPBS,pH7.4,with0.1%BSAand0.0015%sodiumazideasapreservative. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainat-20°Cinundilutedaliquotsforupto12monthsafterdateofreceipt.Avoidrepeatedfreeze/thawcycles. Duringshipment,smallvolumesofantibodywilloccasionallybecomeentrappedinthesealoftheproductvial.Forantibodieswithvolumesof200μlorless,werecommendgentlytappingthevialonahardsurfaceorbrieflycentrifugingthevialonatabletopcentrifugetodislodgeanyliquidinthecontainer"scap. |
| Applications | |
|---|---|
| Application | DetectVEGFReceptor-3usingthisAnti-VEGFReceptor-3AntibodyvalidatedforuseinIC,IH(P)&WB. |
| KeyApplications |
|
| ApplicationNotes | Immunohistochemistryonformalinfixedparaffinsections:1:100-1:400.Hightemperatureantigenretrievalin10mMcitratebuffer(pH6.0)isstronglyrecommended.Blockingwith2%normalserumplus1%BSAinPBSissuggested.PrimaryantibodyshouldbedilutedinPBSwith0.1%BSAonly.TheuseofTritonX-100orexcessblockingcompoundsisnotrecommended. WesternBlot:antibodyrecognizesthreebandsmigratingatapproximately198kDa,94kDaand47kDacorrespondingtothelongandshortformsofthereceptorplusapossIBLebreakdownproduct,respectively.Variationinbandpositionisexpectedduetosignificantvariationinexpressionandglycosylationinvarioustissuesandcelllines.Membraneextractpreparationsandtheliberaluseofproteinaseinhibitorsisstronglyrecommended. Immunocytochemistry:MCF7,SW480andMDA-MBcelllinesarepositivecontrols. Optimalworkingdilutionsmustbedeterminedbytheenduser. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | Raisedagainsta12aminoacidsequencecorrespondingtotheN-terminusofthehumanvascularendothelialgrowthfactorreceptor3[VEGFR3/FLT4]. |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Rabbit |
| Specificity | AB1875isspecificfortheN-terminusofVEGFReceptor3[FLT4]and,thus,itwillrecognizeboththelongandshortformsofthereceptor.Stainingofformalinfixedparaffinembeddedhumantissuesectionsispredominantlylocalizedinthecytoplasm. |
| SpeciesReactivity |
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| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| GeneSymbol |
|
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P35916#ReceptorforVEGFC.Hasatyrosine-proteinkinaseactivity. SIZE:1298aminoacids;145599Da SUBCELLULARLOCATION:Membrane;Single-passtypeImembraneprotein. TISSUESPECIFICITY:Placenta,lung,heart,andkidney,doesnotseemtobeexpressedinpancreasandbrain. DISEASE:SwissProt:P35916#DefectsinFLT4arethecauseofhereditarylymphedemaI[MIM:153100];alsoknownasNonne-MilroylymphedemaorMilroydisease.Hereditarylymphedemaisachronicdisablingconditionwhichresultsinswellingoftheextremitiesduetoalteredlymphaticflow.Patientswithlymphedemasufferfromrecurrentlocalinfectionsandphysicalimpairment.HereditarylymphedemaIshowsautosomaldominantinheritanceandischaracterizedbyonsetusuallyatbirth.&DefectsinFLT4arefoundinjuvenilehemangioma.Juvenilehemangiomasarethemostcommontumorsofinfancy,occurringasmanyas10/%ofallbirths.Thesebenignvascularlesionsenlargerapidlyduringthefirstyearoflifebyhyperplasiaofendothelialcellsandattendantpericytes,andthenspontaneouslyinvoluteoveraperiodofyears,leavingloosefibrofattytissue. SIMILARITY:SwissProt:P35916##Belongstotheproteinkinasesuperfamily.Tyrproteinkinasefamily.CSF-1/PDGFreceptorsubfamily.&Contains7Ig-likeC2-type(immunoglobulin-like)domains.&Contains1proteinkinasedomain. |
| PhysicochemicalInformation |
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| Dimensions |
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| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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