微孔/ABF32 |抗成纤维细胞特异性蛋白1(S100A4)抗体/ABF32/100µ;G
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产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | |
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CatalogueNumber | ABF32 |
Description | Anti-Fibroblast-specificProtein1(S100A4)Antibody |
AlternateNames |
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BackgroundInformation | S100A4,alsoknownasFibroblast-specificProtein1,isamemberoftheCa2+-dependentS100familyofproteinscontaining2EF-handcalcium-bindingmotifs.S100isametastasisfactorthatmayfunctioninmotility,invasion,andtubulinpolymerization.IncreasedexpressionofS100A4hasbeenassociatedwithvarioustypesofcancer. |
ProductInformation | |
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Format | AffinityPurified |
Control |
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Presentation | Purifiedrabbitpolyclonalinbuffercontaining0.1MTris-Glycine(pH7.4),150mMNaClwith0.05%sodiumazide. |
StorageandShippingInformation | |
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StorageConditions | Stablefor1yearat2-8°Cfromdateofreceipt. |
BIOLOGicalInformation | |
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Immunogen | KLH-conjugatedlinearpeptidecorrespondingtotheC-terminusofhumanS100A4. |
Epitope | C-terminus |
Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
Host | Rabbit |
Specificity | ThisantibodyrecognizesS100A4attheC-terminus. |
SpeciesReactivity |
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SpeciesReactivityNote | DemonstratedtoreactwithHuman,Mouse,andRat. PredictedtoreactwithBovine,Canine,andEquinebasedon100%sequencehomology. |
AntibodyType | PolyclonalAntibody |
EntrezGeneNumber | |
EntrezGeneSummary | TheproteinencodedbythisgeneisamemberoftheS100familyofproteinscontaining2EF-handcalcium-bindingmotifs.S100proteinsarelocalizedinthecytoplasmand/ornucleusofawiderangeofcells,andinvolvedintheregulationofanumberofcellularprocessessuchascellcycleprogressionanddifferentiation.S100genesincludeatleast13memberswhicharelocatedasaclusteronchromosome1q21.Thisproteinmayfunctioninmotility,invasion,andtubulinpolymerization.Chromosomalrearrangementsandalteredexpressionofthisgenehavebeenimplicatedintumormetastasis.Multiplealternativelysplicedvariants,encodingthesameprotein,havebeenidentified.[providedbyRefSeq,Jul2008]. |
GeneSymbol |
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PurificationMethod | AffinityPurfied |
UniProtNumber | |
UniProtSummary | SUBUNITSTRUCTURE:Homodimer.InteractswithPPFIBP1inacalcium-dependentmode. TISSUESPECIFICITY:Ubiquitouslyexpressed. SEQUENCESIMILARITIES:BelongstotheS-100family. Contains2EF-handdomains. |
MolecularWeight | ~12kDaobserved |
PhysicochemicalInformation |
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Dimensions |
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MaterialsInformation |
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MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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