Millipore/AB15328 | Anti-Olig2 Antibody/AB15328/100 µg
市场价:
¥6980.00
美元价:
4188.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | |
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CatalogueNumber | AB15328 |
BrandFamily | Chemicon® |
TradeName |
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Description | Anti-Olig2Antibody |
ProductInformation | |
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Format | AffinityPurified |
Presentation | LiquidinPBScontaining0.1%sodiumazide. |
StorageandShippingInformation | |
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StorageConditions | Maintainat2-8degCinundilutedaliquotsforupto6monthsafterdateofreceipt. |
Applications | |
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Application | ThisAnti-Olig2AntibodyisvalidatedforuseinWBforthedetectionofOlig2. |
KeyApplications |
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BIOLOGicalInformation | |
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Immunogen | Syntheticpeptidefromrat. |
Host | Rabbit |
Specificity | OligodendrocyteMarkerOlig2.ByWesternblottheantibodyrecognizesabandat~32kDainratbrainextract. |
SpeciesReactivity |
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AntibodyType | PolyclonalAntibody |
EntrezGeneNumber | |
EntrezGeneSummary | Thisgeneencodesabasichelix-loop-helixtranscriptionfactorwhichisexpressedinoligodendroglialtumorsofthebrain.TheproteinisanessentialregulatorofventralneuroectodermalProgenitorcellfate.Thegeneisinvolvedinachromosomaltranslocationt(14;21)(q11.2;q22)associatedwithT-cellacutelymphoblasticleukemia.Itschromosomallocationiswithinaregionofchromosome21whichhasbeensuggestedtoplayaroleinlearningdeficitsassociatedwithDownsyndrome. |
GeneSymbol |
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PurificationMethod | ImmunoAffinityPurified |
UniProtNumber | |
UniProtSummary | FUNCTION:SwissProt:Q13516#Requiredforoligodendrocyteandmotorneuronspecificationinthespinalcord,aswellasforthedevelopmentofsomaticmotorneuronsinthehindbrain.CooperateswithOLIG1toestablishthepMNdomainoftheembryonicneuraltube.AntagoNISTofV2interneuronandofNKX2-2-inducedV3interneurondevelopment(Bysimilarity). SIZE:323aminoacids;32385Da SUBUNIT:InteractswithNKX2-2(Bysimilarity). SUBCELLULARLOCATION:Nucleus(Bysimilarity).Cytoplasm(Bysimilarity).Note=TheNLScontainedinthebHLHdomaincouldbemaskedinthenativeformandtranslocationtothenucleuscouldbemediatedbyinteractioneitherwithclassEbHLHpartnerproteinorwithNKX2-2(Bysimilarity). TISSUESPECIFICITY:Expressedinthebrain,inoligodendrocytes.Stronglyexpressedinoligodendrogliomas,whileexpressionisweaktomoderateinastrocytomas.Expressioninglioblastomashighlyvariable. DOMAIN:SwissProt:Q13516ThebHLHisessentialforinteractionwithNKX2-2(Bysimilarity).DISEASE:SwissProt:Q13516#AchromosomalaberrationinvolvingOLIG2maybeacauseofaformofT-cellacutelymphoblasticleukemia(T-ALL).Translocationt(14;21)(q11.2;q22)withTCRA. SIMILARITY:Contains1basichelix-loop-helix(bHLH)domain. |
PhysicochemicalInformation |
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Dimensions |
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MaterialsInformation |
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MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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