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Millipore/MAB3402C3 | Anti-GFAP Antibody, Cy3 Conjugate/MAB3402C3/100 µL
Millipore/MAB3402C3 | Anti-GFAP Antibody, Cy3 Conjugate/MAB3402C3/100 µL
市场价：
¥8020.00
美元价：
4812.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | MAB3402C3 |
| Description | Anti-GFAPAntibody,Cy3Conjugate |
| AlternateNames |
|
| BackgroundInformation | Glialfibrillaryacidicproteinisaclass-IIIintermediatefilament.GFAPisthemainconstituentofintermediatefilamentsinastrocytesandservesasacellspecificMarkerthatdistinguishesdifferentiatedastrocytesfromotherglialcellsduringthedevelopmentofthecentralnervoussystem. |
| ProductInformation | |
|---|---|
| Format | Cy3 |
| Control |
|
| Presentation | PurifiedmousemonoclonalIgG1conjugatedtoCy3inPBSwith0.1%sodiumazideand15mg/mLBSA. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainrefrigeratedat2-8°Cprotectedfromlightinundilutedaliquotsforupto6monthsfromdateofreceipt. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | Purifiedglialfilamentprotein(Debus,E.,1983). |
| Host | Mouse |
| Specificity | TheantibodyreactswithmouseGFAP.Intissuesectionsthis antibodystainsastrocytesandBergmangliacells(Debus,E.,1983). |
| Isotype | IgG1 |
| SpeciesReactivity |
|
| SpeciesReactivityNote | DemonstratedtoreactwithMouse.PredictedtoreactwithHuman,Rat,Porcine,andChickenbasedon100%sequencehomology. |
| AntibodyType | MonoclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | Thisgeneencodesoneofthemajorintermediatefilamentproteinsofmatureastrocytes.Itisusedasamarkertodistinguishastrocytesfromotherglialcellsduringdevelopment.MutationsinthisgenecauseAlexanderdisease,araredisorderofastrocytesinthecentralnervoussystem.Alternativesplicingresultsinmultipletranscriptvariantsencodingdistinctisoforms.[providedbyRefSeq]. |
| GeneSymbol |
|
| PurificationMethod | ProteinAPurfied |
| UniProtNumber | |
| UniProtSummary | FUNCTION:GFAP,aclass-IIIintermediatefilament,isacell-specificmarkerthat,duringthedevelopmentofthecentralnervoussystem,distinguishesastrocytesfromotherglialcells. SIZE:432aminoacids;49880Da SUBUNIT:Isoform3interactswithN-terminusofPSEN1. SUBCELLULARLOCATION:Cytoplasm.Note=Associatedwithintermediatefilaments. DISEASE:DefectsinGFAPareacauseofAlexanderdisease[MIM:203450].Alexanderdiseaseisararedisorderofthecentralnervoussystem.ItisaprogressiveleukoencephalopathywhosehallmarkisthewidespreadaccumulationofRosenthalfiberswhicharecytoplasmicinclusionsinastrocytes.Themostcommonformaffectsinfantsandyoungchildren,andischaracterizedbyprogressivefailureofcentralmyelination,usuallyleADIngtodeathusuallywithinthefirstdecade.InfantswithAlexanderdiseasedevelopaleukoencephalopathywithmacrocephaly,seizures,andpsychomotorretardation.Patientswithjuvenileoradultformstypicallyexperienceataxia,bulbarsignsandspasticity,andamoreslowlyprogressivecourse. SIMILARITY:Belongstotheintermediatefilamentfamily. |
| MolecularWeight | 50kDaObserved(UsingunconjugatedantibodyMAB3402) |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
|---|
品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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