微孔/ABC36 |抗豌豆-15抗体/ABC36/100µ;G
市场价:
¥0.00
美元价:
0.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | |
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CatalogueNumber | ABC36 |
Description | Anti-PEA-15Antibody |
AlternateNames |
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BackgroundInformation | PEA-15isa15kDacytoplasmicproteinwhichisabundantlyexpressedinastrocytes,althoughithasbeendetectedinavarietyofothercellsincludingthoseoftheheartandmuscle.ItmaybephosphorylatedonSer104byproteinkinaseCandonSer116byCAMKII,inacalcium-dependentmanner,inresponsetovarioushormonesandneurotransmitters.PEA-15alsocontainsanN-terminaldeatheffectordomain(DED)whichischaracteristicofproteinsthatregulateapoptosis.PreviousstudieshavereportedthatitinhibitsapoptosisinducedbythesignalingofTNFαinastrocytes.However,itisbecomingincreasinglyclearthatPEA-15isamultifunctionalproteinaffectingdiversecellularprocesses,possIBLybyitsmodulationoftheMAPkinasesignalingpathway.PreviousstudieshavedemonstratedthatPEA-15bindstoERKkinaseinthecytoplasm,andpreventstheactivationandnucleartranslocationofERK.Consequently,PEA-15blockstranscriptionaleventsandcellularprocessesmediatedbyERKanditsnucleartargetElk-1. |
ProductInformation | |
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Format | Purified |
Control |
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Presentation | Purifiedrabbitpolyclonalinbuffercontaining0.1MTris-Glycine(pH7.4),150mMNaClwith0.05%sodiumazide. |
StorageandShippingInformation | |
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StorageConditions | Stablefor1yearat2-8°Cfromdateofreceipt. |
BIOLOGicalInformation | |
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Immunogen | GST-taggedrecombinantproteincorrespondingtohumanPEA-15. |
Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
Host | Rabbit |
SpeciesReactivity |
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AntibodyType | PolyclonalAntibody |
EntrezGeneNumber | |
GeneSymbol |
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PurificationMethod | ProteinAPurfied |
UniProtNumber | |
MolecularWeight | ~17kDaobserved.Anuncharacterizedbandappearsat~32and~260kDainsomelysates. |
PhysicochemicalInformation |
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Dimensions |
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MaterialsInformation |
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MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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