Millipore/07-329 |抗乙酰基组蛋白H4(Lys16)抗体/07-329/100µ;L
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¥0.00
美元价:
0.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | 07-329 |
| BrandFamily | Upstate |
| TradeName |
|
| Description | Anti-acetyl-HistoneH4(Lys16)Antibody |
| AlternateNames |
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| BackgroundInformation | HistoneH4isoneofthe5mainhistoneproteinsinvolvedinthestructureofchromatinineukaryoticcells.FeaturingamainglobulardomainandalongNterminaltailH4isinvolvedwiththestructureofthenucleosomesofthe"beadsonastring"structure.AcetylationofhistoneH4occursatseveraldifferentlysinepositionsinthehistonetailandisperformedbyafamilyofenzymesknownasHistoneAcetylTransferases(HATs). |
| ProductInformation | |
|---|---|
| Format | AffinityPurified |
| Control |
|
| Presentation | Purifiedrabbitpolyclonalinbuffercontaining0.1MTris-Glycine(pH7.4)150mMNaClwith0.05%sodiumazide. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Stablefor1yearat2-8°Cfromdateofreceipt. Formaximumrecoveryofproduct,centrifugethevialpriortoremovingthecap. |
| Applications | |
|---|---|
| Application | Anti-acetyl-HistoneH4(Lys16)Antibodyisarabbitpolyclonalantibodyfordetectionofacetyl-HistoneH4(Lys16)alsoknownasH4K16Ac,HistoneH4(acetylK16&hasbeenpublishedandvalidatedinChIP,WB,Mplex,PIA,DB,ChIP-seq. |
| KeyApplications |
|
| ApplicationNotes | ImmunocytochemistryAnalysis:A1:500dilutionfromarepresentativelotdetectedAcetyl-HistoneH4(Lys16)inHeLa,A431andNIH/3T3cells. ChromatinImmunoprecipitation(ChIP)Analysis:1µgfromarepresentativelotimmunoprecipitatedAcetyl-HistoneH4(Lys16)in1µLofHeLacelllysate. DotBlotAnalysis:A1:5,000dilutionfromarepresentativelotdetectedAcetyl-HistoneH4(Lys16)inanAbsurance™HistoneH3AntibodySpecificityArray(Cat.No.16-667)andanAbsurance™HistoneH2A,H2B,H4AntibodySpecificityArray(Cat.No.16-665). Multiplexing(MPLX):ThisantibodyspecificallyrecognizeshistoneH4acetylatedonLys16byLuminex®assay. PeptideInhibitionAssay(PIA):ThisantibodypeptideblockedonHeLacellextracts. ChIP-SeqAnalysis:Arepresentativelotofthisantibodywasusedbytwoindependent laboratoriesforChIP-Seq(StromeandAhringerLaboratory,UCSantaCruz/Universityof CambridgeandMitziKurodaLaboratory,HarvardMedicalSchool)SeeEgelhofer,T.A.,etal.(2011). |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | Ovalbumin-conjugated,syntheticpeptide(…GAAcKRH…)inwhichAcKcorrespondstoresidue16ofyeasthistoneH4. |
| Epitope | Lys16 |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Rabbit |
| Isotype | IgG |
| SpeciesReactivity |
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| SpeciesReactivityNote | Broadspeciescross-reactivityisexpected. |
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| GeneSymbol |
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| Modifications |
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| PurificationMethod | AffinityPurfied |
| UniProtNumber | |
| MolecularWeight | 10kDa |
| PhysicochemicalInformation |
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| Dimensions |
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| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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