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Millipore/07-680 | Anti-Histone H2B Antibody, testis variant/07-680/100 µL
Millipore/07-680 | Anti-Histone H2B Antibody, testis variant/07-680/100 µL
市场价：
¥7800.00
美元价：
4680.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | 07-680 |
| Replaces | MABE15 |
| BrandFamily | Upstate |
| TradeName |
|
| Description | Anti-HistoneH2BAntibody,testisvariant |
| ProductInformation | |
|---|---|
| Format | Serum |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | stable2yearsat-20°Cfromdateofshipment |
| Applications | |
|---|---|
| Application | Anti-HistoneH2BAntibody,testisvariantisaRabbitPolyclonalAntibodyfordetectionofHistoneH2BalsoknownasHistoneH2B&hasbeentestedinWB. |
| KeyApplications |
|
| BIOLOGicalInformation | |
|---|---|
| Immunogen | KLH-conjugated,syntheticpeptidespanningaminoacids7-17(...GATISKKGFKK...)ofhumantestis/spermspecifichistoneH2B |
| Host | Rabbit |
| Specificity | histoneH2B,testisvariant |
| SpeciesReactivity |
|
| SpeciesReactivityNote | Predictedtocross-reactwithratbasedonsequencehomology |
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | HistonesarebasicnuclearproteinsthatareresponsIBLeforthenucleosomestructureofthechromosomalfiberineukaryotes.Nucleosomesconsistofapproximately146bpofDNAwrappedaroundahistoneoctamercomposedofpairsofeachofthefourcorehistones(H2A,H2B,H3,andH4).Thechromatinfiberisfurthercompactedthroughtheinteractionofalinkerhistone,H1,withtheDNAbetweenthenucleosomestoformhigherorderchromatinstructures.Thisgeneisintronlessandencodesatestis/sperm-specificmemberofthehistoneH2Bfamily.Transcriptsfromthisgenecontainapalindromicterminationelement. |
| GeneSymbol |
|
| PurificationMethod | Antiserum |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:Q96A08#Corecomponentofnucleosome.NucleosomeswrapandcompactDNAintochromatin,limitingDNAaccessibilitytothecellularmachinerieswhichrequireDNAasatemplate.Histonestherebyplayacentralroleintranscriptionregulation,DNArepair,DNAreplicationandchromosomalstABIlity.DNAaccessibilityisregulatedviaacomplexsetofpost-translationalmodificationsofhistones,alsocalledhistonecode,andnucleosomeremodeling. SIZE:127aminoacids;14167Da SUBUNIT:ThenucleosomeisahistoneoctamercontainingtwomoleculeseachofH2A,H2B,H3andH4assembledinoneH3-H4heterotetramerandtwoH2A-H2Bheterodimers.Theoctamerwrapsapproximately147bpofDNA. SUBCELLULARLOCATION:Nucleus. TISSUESPECIFICITY:Transcribedexclusivelyintestis,andthecorrespondingproteinisalsopresentinmaturesperm. PTM:MonoubiquitinationofLys-122bytheRNF20/40complexgivesaspecifictagforepigenetictranscriptionalactivationandisalsoprerequisiteforhistoneH3"Lys-4"and"Lys-79"methylation.ItalsofunctionscooperativelywiththeFACTdimertostimulateelongationbyRNApolymeraseII. SIMILARITY:SwissProt:Q96A08##BelongstothehistoneH2Bfamily. |
| MolecularWeight | Mr15kDa |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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