当前位置：
首页
>
产品中心 >
Functional_antibody >
Millipore/IHCR1006-6 | Anti-Nestin Antibody, prediluted, clone rat-401/IHCR1006-6/6 mL
Millipore/IHCR1006-6 | Anti-Nestin Antibody, prediluted, clone rat-401/IHCR1006-6/6 mL
商品编号：
IHCR1006-6
品牌：
密理博
市场价：
¥0.00
美元价：
0.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | IHCR1006-6 |
| BrandFamily | Chemicon® |
| TradeName |
|
| Description | Anti-NestinAntibody,prediluted,clonerat-401 |
| Overview | Nestinisalargeintermediatefilamentprotein(classTypeVI)expressedduringdevelopmentandinmyotendinousandneuromuscularjunctions.Nestinexpressionisrestricted,typicallydisappearingbyE18.NestinisthoughttobeareasonableneuronalMarker;however,recentstudieshavefoundnestinexpressioninothercelltypessuchasendothelialcells(MokryandNemecek,1998)..Nestinidentifiesthemostprimitiveneuroepitheliumbutalsoidentifiesmanyotherembryonictissues,soitisnotspecificforCNS.NestinexpressionisseeninalmostallGMBs(Glioblastomamultiformes)andmanymelanomas(bothprimaryandmetastatic)butnotinanymetastaticcarcinomas. |
| ProductInformation | |
|---|---|
| Format | Purified |
| Presentation | LiquiddilutedinPBS,pH7.2withstABIlizers,0.2%Tween20,and0.1%ProClin300aspreservative. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainat2-8°C.Refertovialforexpirationdating. |
| Applications | |
|---|---|
| Application | Anti-NestinAntibody,prediluted,clonerat-401detectslevelofNestin&hasbeenpublished&validatedforuseinIH(P). |
| KeyApplications |
|
| BIOLOGicalInformation | |
|---|---|
| Immunogen | Nestinpurifiedfromembryonicratspinalcord. |
| Clone | rat-401 |
| Host | Mouse |
| Specificity | RodentNestinproteinconfirmedwithratandmouse.Rat-401isnotreactivewithhumannestinprotein. |
| Isotype | IgG1 |
| SpeciesReactivity |
|
| AntibodyType | MonoclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | NestinisanintermediatefilamentproteinthatwasfirstidentifiedwithamonoclonalantibodybyHockfieldandMcKay(1985)[PubMed4078630].Itisexpressedpredominantlyinstemcellsofthecentralnervoussystemintheneuraltube.Uponterminalneuraldifferentiation,nestinisdownregulatedandreplacedbyneurofilaments.[suppliedbyOMIM] |
| GeneSymbol |
|
| Non-ReactiveSpecies |
|
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P48681#MayplayaroleinthetraffickinganddistributionofIFproteinsandpotentiallyothercellularfactorstodaughtercellsduringProgenitorcelldivision(Bysimilarity). SIZE:1621aminoacids;177439Da SUBUNIT:InteractswithFHOD3(Bysimilarity). TISSUESPECIFICITY:CNSstemcells. DEVELOPMENTALSTAGE:Uponterminalneuraldifferentiation,nestinisdown-regulatedandreplacedbyneurofilaments. SIMILARITY:SwissProt:P48681##Belongstotheintermediatefilamentfamily. |
| StemCellType |
|
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
|---|
品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
联络我们
