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当前位置: 首页 > 产品中心 > Functional_antibody > Millipore/MAB1687 | Anti-Vimentin Antibody, clone 43BE8/MAB1687/100 µL
商品详细Millipore/MAB1687 | Anti-Vimentin Antibody, clone 43BE8/MAB1687/100 µL
Millipore/MAB1687 | Anti-Vimentin Antibody, clone 43BE8/MAB1687/100 µL
Millipore/MAB1687 | Anti-Vimentin Antibody, clone 43BE8/MAB1687/100 µL
商品编号: MAB1687
品牌: 密理博
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberMAB1687
BrandFamilyChemicon®
TradeName
  • Chemicon
DescriptionAnti-VimentinAntibody,clone43BE8
ProductInformation
FormatAscites
PresentationLiquid
StorageandShippingInformation
StorageConditionsMaintainat-20°Cinundilutedaliquotsforupto12months.Avoidrepeatedfreeze/thawcycles.
Applications
ApplicationThisAnti-VimentinAntibody,clone43BE8isvalidatedforuseinIC,IH(P)forthedetectionofVimentin.
KeyApplications
  • Immunocytochemistry
  • Immunohistochemistry(Paraffin)
ApplicationNotesImmunohistochemistry:1:500-1:2,000onparaffinembeddedsections(ABCperoxidase)fixedwithalcohol(e.g.Carnoy)witha2"pronasedigestion.Aldehydefixationisnotrecommended.

Immunocytochemistry:1:100-1:200cellsinvitro(IFA)fixedinicecoldabsolutemethanoloracetone.

Optimalworkingdilutionsmustbedeterminedbytheenduser.
BIOLOGicalInformation
Clone43BE8
HostMouse
SpecificityVimentin(58kD).Reactsinimmunocytochemicalassayswithallmesenchymalcells(fibroblasts,Scwanncells,endothelialcells,smoothmusclecells,etc.).
IsotypeIgM
SpeciesReactivity
  • Human
  • Monkey
AntibodyTypeMonoclonalAntibody
EntrezGeneNumber
EntrezGeneSummaryAlongwiththeMICROFILaments(actins)andmicrotubules(tubulins),theintermediatefilamentsrepresentathirdclassofwell-characterizedcytoskeletalelements.Thesubunitsdisplayatissue-specificpatternofexpression.Desmin(MIM125660)isthesubunitspecificformuscleandvimentinthesubunitspecificformesenchymaltissue.[suppliedbyOMIM]
GeneSymbol
  • VIM
  • FLJ36605
  • Vimentin.
  • vimentin
UniProtNumber
UniProtSummaryFUNCTION:SwissProt:P08670#Vimentinsareclass-IIIintermediatefilamentsfoundinvariousnon-epithelialcells,especiallymesenchymalcells.
SIZE:466aminoacids;53652Da
SUBUNIT:Homopolymer.ComponentofacomplexcomposedatleastofACTB,AP2M1,AP2A1,AP2A2,MEGF10andVIM.InteractswithHCVcoreprotein.
TISSUESPECIFICITY:Highlyexpressedinfibroblasts,someexpressioninT-andB-lymphocytes,andlittleornoexpressioninBurkitt"slymphomacelllines.Expressedinmanyhormone-independentmammarycarcinomacelllines.
PTM:Oneofthemostprominentphosphoproteinsinvariouscellsofmesenchymalorigin.Phosphorylationisenhancedduringcelldivision,atwhichtimevimentinfilamentsaresignificantlyreorganized.
SIMILARITY:SwissProt:P08670##Belongstotheintermediatefilamentfamily.
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。