密理博/AB1603 |抗磷酸丝氨酸抗体/AB1603/50µ；G
市场价：
¥6580.00
美元价：
3948.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | AB1603 |
| BrandFamily | Chemicon® |
| TradeName |
|
| Description | Anti-PhosphoserineAntibody |
| BackgroundInformation | Cellularresponsestoavarietyofextracellularsignalsoccurthroughphosphorylationordephosphorylationofintracellularproteins.Abnormalproteinphosphorylationmaybeinvolvedintheprogressionofnumerousdiseases,includingmanyformsofcancer,immunesystemdysfunctionandcardiovasculardisease.Suchchangesinproteinphosphorylationmaybedetectedbyimmunocytochemicalmappingofcellslabeledwithanti-phosphoserineoranti-phosphothreonineantibodiesandcanbecorrelatedwithcellular,electrophysiologicalorbehavioralstatechanges. |
| ProductInformation | |
|---|---|
| Format | AffinityPurified |
| Control |
|
| Presentation | Purifiedrabbitseruminbuffercontaining50%glycerol. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Stableforupto6monthsat-20°Cinundilutedaliquotsfromdateofreceipt.Duringshipment,smallvolumesofproductwilloccasionallybecomeentrappedinthesealoftheproductvial.Forproductswithvolumesof200uLorless,werecommendgentlytappingthevialonahardsurfaceorbrieflycentrifugingthevialinatabletopcentrifugetodislodgeanyliquidinthecontainer"scap. |
| Applications | |
|---|---|
| Application | Anti-PhosphoserineAntibodydetectslevelofPhosphoserine&hasbeenpublished&validatedforuseinELISA,IH,IP&WB. |
| KeyApplications |
|
| ApplicationNotes | Immunoprecipitation(tissueextracts): 10-20μganti-pS/mgproteinwasusedfromapreviouslot. Notethatthiswillimmunoprecipitateallphosphoserineproteinsintheextracts.Ifusingpurifiedproteinexactscontainingonlytheproteinofinterest,antibodyamountsshouldbedecreasedto5μg/500μLofextracts.Optimalconcentrationsmustbedeterminedexperimentally. ELISA(kinaseassay): Apreviouslotofthisanitbodywasusedata1:250-1:500dilution. Immunohistochemistry: Apreviouslotofthisantibodywasusedata1:50dilution. Astheantibodydetectsallphosphoserines,anyphosphorylatedserineproteinorpeptidecanbeusedtoblockantibodystaining. Typicallya10MexcessofpeptideisusedinTrisbasedbuffers. WesternBlotAnalysis: 1:500dilutionofapreviouslot Optimalworkingdilutionsmustbedeterminedbyenduser. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | KeyholeLimpetHemocyanin(KLH)-conjugatedphosphoserineconjugates. |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Rabbit |
| Specificity | Recognizesphosphoserine,peptidyl-phosphoserine,andserine-phosphorylatedproteins.DoesnotcrossreactwithATP,phosphotyrosine,peptidylphosphothreonineandserine.Slightcrossreactivitywithfreephosphothreonine.ReADIlyreactswithknownphosphoproteinssuchasphosvitinandalphacasein.Anti-phosphoserineisspeciesindependentinreactivity |
| SpeciesReactivity |
|
| SpeciesReactivityNote | Anti-phosphoserineisspeciesindependent. |
| AntibodyType | PolyclonalAntibody |
| Modifications |
|
| PurificationMethod | Phosphoserineaffinitychromatography |
| MolecularWeight | Dependentuponthemolecularweightoftheserinephosphorylatedproteinbeingdetected. |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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