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Millipore/17-499 | Phosphorylation Explorer Pack Sample Kit/17-499/1 kit
Millipore/17-499 | Phosphorylation Explorer Pack Sample Kit/17-499/1 kit
市场价：
¥6980.00
美元价：
4188.00
产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | 17-499 |
| BrandFamily | Upstate |
| TradeName |
|
| Description | PhosphorylationExplorerPackSampleKit |
| BackgroundInformation | 4G10®Platinum Thedevelopmentoftheanti-phosphotyrosine,clone4G10®in1989wasamonumentaldiscoveryforresearchers.4G10®wasthefirstandisthebestsinglemonoclonalantibodyforthedetectiontyrosinephosphorylation.4G10®iswellknownforitssensitivityanditsABIlitytodetectmultipletyrosinephosphorylationsonnumeroussubstrates.Ithasbeenvalidatedbythousandsofscientificandmedicalresearchersinvirtuallyeveryapplicationandtyrosinetargetoverthepast2decades.Toimproveonsomethingthathundredhavetriedandnoonehassucceeded,wepooled4G10®withthenextmosthighlyregardedanti-phosphotyrosine,clonePY20tomake4G10®Platinum.PY20itselfisaverypoorsubstitutefor4G10®,butitsadditiveeffectallowforagreaterlevelofdetectiononmoresubstratesthateven4G10®alonewasnotcapableof. 4A4 TheidentificationofproteinphosphorylationasaregulatorymechanismoriginatedfromstudiesbyFischerandKrebsinthemid1950sthatlaterearnedthemthe1992Nobelprize.Itisthemajormechanismfortheregulationofdiversecellularprocessesincludingcelldivision,proteinsynthesis,transcriptionalregulationandneurotransmission.Thesteadystatephosphorylationofanygivensubstrateisgovernedbytheopposingactivitiesofkinasesandphosphatases.Itisnowbelievedthatathirdofalleukaryoticcellularproteinsarephosphorylatedandthatthemajorityofallphosphorylationeventsoccuronserineandthreonineresidues(greaterthan95%). |
| ProductInformation | |
|---|---|
| Components |
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| StorageandShippingInformation | |
|---|---|
| StorageConditions | Seeindividualcomponentsforstorage/handlingconditions. |
| Applications | |
|---|---|
| Application | ThisAntibodypackcontainsAnti-phosphotyrosineAntibody,Anti-PhosphoserineAntibody,validatedforuseinWB,IF,Flow,IHC,ELISA,ICC. |
| KeyApplications |
|
| BIOLOGicalInformation | |
|---|---|
| Clone | 4G10®Platinumand4A4 |
| Host | Mouse |
| Modifications |
|
| MolecularWeight | Dependentuponthemolecularweightofthetyrosinephosphorylatedproteinbeingdetected. |
| PhysicochemicalInformation |
|---|
| Dimensions |
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| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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