当前位置:
首页
>
产品中心 >
Functional_antibody >
Millipore/05-643 |抗磷酸化GSK3β(Ser9)抗体,克隆2D3/05-643/100µ;G

Millipore/05-643 |抗磷酸化GSK3β(Ser9)抗体,克隆2D3/05-643/100µ;G
市场价:
¥7180.00
美元价:
4308.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | |
---|---|
CatalogueNumber | 05-643 |
Replaces | 04-1075 |
BrandFamily | Upstate |
TradeName |
|
Description | Anti-phospho-GSK3β(Ser9)Antibody,clone2D3 |
ProductInformation | |
---|---|
Format | Purified |
Presentation | 100µgofthiophilicandsizeexclusionchromatographypurifiedmouseIgG1κin100µLofantibodystoragebuffer(PBSwithPEG,Sucrose,and0.09%sodiumazide)and50%glycerol. |
StorageandShippingInformation | |
---|---|
StorageConditions | 2yearsat-20°C |
Applications | |
---|---|
Application | Anti-phospho-GSK3β(Ser9)Antibody,clone2D3isanantibodyagainstphospho-GSK3β(Ser9)foruseinEMSA&WB. |
KeyApplications |
|
BIOLOGicalInformation | |
---|---|
Immunogen | peptidecorrespondingtoaminoacids6-12(RTT[pS]AE)ofhumanGSK3beta |
Clone | 2D3 |
Host | Mouse |
Specificity | GSK3beta |
Isotype | IgG1κ |
SpeciesReactivity |
|
AntibodyType | MonoclonalAntibody |
EntrezGeneNumber | |
EntrezGeneSummary | Glycogensynthasekinase-3(GSK3)isaproline-directedserine-threoninekinasethatwasinitiallyidentifiedasaphosphorylatingandinactivatingglycogensynthase.Twoisoforms,alpha(GSK3A;MIM606784)andbeta,showahighdegreeofaminoacidhomology(StambolicandWoodgett,1994[PubMed7980435]).GSK3Bisinvolvedinenergymetabolism,neuronalcelldevelopment,andbodypatternformation(Plyteetal.,1992[PubMed1333807]).[suppliedbyOMIM] |
GeneSymbol |
|
Modifications |
|
PurificationMethod | Thiophilicadsorptionchromatography |
UniProtNumber | |
UniProtSummary | FUNCTION:SwissProt:P49841#ParticipatesintheWntsignalingpathway.Implicatedinthehormonalcontrolofseveralregulatoryproteinsincludingglycogensynthase,MYBandthetranscriptionfactorJUN.PhosphorylatesJUNatsitesproximaltoitsDNA-bindingdomain,therebyreducingitsaffinityforDNA. SIZE:420aminoacids;46744Da SUBUNIT:Monomer(Bysimilarity).InteractswithNINandCABYR. TISSUESPECIFICITY:Expressedintestis,thymus,prostateandovaryandweaklyexpressedinlung,brainandkidney. PTM:PhosphorylatedbyAKT1andILK1. SIMILARITY:SwissProt:P49841##Belongstotheproteinkinasesuperfamily.CMGCSer/Thrproteinkinasefamily.GSK-3subfamily.&Contains1proteinkinasedomain. |
MolecularWeight | 46kDa(GSK3β)and51kDa(GSK3α) |
PhysicochemicalInformation |
---|
Dimensions |
---|
MaterialsInformation |
---|
MaterialsInformation |
---|
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
联络我们