密理博/FCMAB198F |密标™ 抗CD54-FITC抗体,克隆6.5B5/FCMAB198F/100试验
市场价:
¥5340.00
美元价:
3204.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | |
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CatalogueNumber | FCMAB198F |
TradeName |
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Description | Milli-Mark™Anti-CD54-FITCAntibody,clone6.5B5 |
AlternateNames |
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BackgroundInformation | TheCD54antigenisasinglechainglycoproteinwithamolecularmassof90kDa(Springer,1990).Itisthehumanintercellularadhesionmolecule-1(ICAM-1)belongingtotheimmunoglobulinsupergenefamily.TheligandforICAM-1isLFA-1(leucocytefunctionassociated-1protein)(Berendt,1992).ICAM-1iswidelyexpressedonmanycelltypes,althoughthedegreeofexpressionbyunstimulatedrestingcellsvaries.AsacellularactivationantigentheexpressionofICAM-1isup-regulateduponcellactivation,beinginducedparticularlyinresponsetocytokinessuchasinterleukin-1,tumornecrosisfactor,andinterferon-(Berendt,1992;Wellicome,1990;Thornhill,1990).ICAM-1mightbeareceptorforrhinovirus(Staunton,1989).Inrejectingkidneystheantibodystainsallinfiltratingcellsstronglyaswellasglomerulusepithelium,endotheliumoncapillaries,largevessels,andmesangium(Waugh,1989). |
ProductInformation | |
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Format | FITC |
Control |
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Presentation | PurifiedMousemonoclonalIgG1conjugatedtoFITCin0.05MTris-HClbufferwith1%BSA,SodiumAzideat0.097%atpH7.2. |
StorageandShippingInformation | |
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StorageConditions | Maintainrefrigeratedat2-8°Cprotectedfromlightinundilutedaliquotsforupto6monthsfromdateofreceipt. |
Applications | |
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Application | Milli-MarkAnti-CD54-FITCAntibody,clone6.5B5isanantibodyagainstCD54foruseinFC. |
KeyApplications |
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BIOLOGicalInformation | |
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Immunogen | TNF-activatedhumanumbilicalveinendothelialcells |
Clone | 6.5B5 |
Host | Mouse |
Specificity | AntibodyrecognizesHumanCD54antigen. |
Isotype | IgG1κ |
SpeciesReactivity |
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AntibodyType | MonoclonalAntibody |
EntrezGeneNumber | |
EntrezGeneSummary | Thisgeneencodesacellsurfaceglycoproteinwhichistypicallyexpressedonendothelialcellsandcellsoftheimmunesystem.ItbindstointegrinsoftypeCD11a/CD18,orCD11b/CD18andisalsoexploitedbyRhinovirusasareceptor. |
PurificationMethod | ProteinAPurfied |
UniProtNumber | |
UniProtSummary | ICAMproteinsareligandsfortheleukocyteadhesionproteinLFA-1(integrinalpha-L/beta-2).Duringleukocytetrans-endothelialmigration,ICAM1engagementpromotestheassemblyofendothelialapicalcupsthroughSGEFandRHOGactivation.Incaseofrhinovirusinfectionactsasacellularreceptorforthevirus. |
MolecularWeight | 90kDa(Springer,1990) |
PhysicochemicalInformation |
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Dimensions |
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MaterialsInformation |
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MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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