Millipore/CBL242 |抗葡萄糖转运蛋白GLUT-1抗体，CT/CBL242/100µ；G
市场价：
¥5960.00
美元价：
3576.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | CBL242 |
| BrandFamily | Chemicon® |
| TradeName |
|
| Description | Anti-GlucoseTransporterGLUT-1Antibody,CT |
| ProductInformation | |
|---|---|
| Format | AffinityPurified |
| Control |
|
| Presentation | Thepolyclonalispresentedinphosphatebufferedsalinecontaining10mMsodiumazide.Werecommendthateachlaboratorydetermineanoptimumworkingtitreforuseinitsparticularapplication. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Forusewithin1monthofpurchasestoreat+4°C,forlongtermstoragealiquotantibodyintosmallvolumesandstoreat-20°Cforuptooneyear. |
| Applications | |
|---|---|
| Application | Anti-GlucoseTransporterGLUT-1Antibody,C-terminusdetectslevelofGlucoseTransporterGLUT-1&hasbeenpublished&validatedforuseinIP&WB. |
| KeyApplications |
|
| ApplicationNotes | WesternblotanalysisofGLUT-1activityinADIposeandmuscletissue(5μg/ml) ImmunoprecipitationofGLUT-1(5μg/ml) Optimalworkingdilutionsmustbedeterminedbytheenduser. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | 12aminoacidpeptideoftheC-terminusofhGLUT-1{LFHPLGADSQV}conjugatedtoKLH |
| Epitope | C-terminus |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Rabbit |
| Specificity | Specificforhumanglucosetransporter1frommuscleandadiposetissue.Doesnotcross-reactwithGLUT-4.Themolecularweightoftheglucosetransporterprecipitatedbytheserumisapproximately46kDa. |
| SpeciesReactivity |
|
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | Glucosetransportersareintegralmembraneglycoproteinsinvolvedintransportingglucoseintomostcells.GLUT1isamajorglucosetransporterinthemammalianblood-brainbarrier.Itispresentathighlevelsinprimateerythrocytesandbrainendothelialcells.[suppliedbyOMIM] |
| GeneSymbol |
|
| PurificationMethod | ImmunoAffinityPurified |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P11166#Facilitativeglucosetransporter.ThisisoformmayberesponsIBLeforconstitutiveorbasalglucoseuptake.Hasaverybroadsubstratespecificity;cantransportawiderangeofaldosesincludingbothpentosesandhexoses. SIZE:492aminoacids;54084Da SUBCELLULARLOCATION:Cellmembrane;Multi-passmembraneprotein(Bysimilarity).Melanosome.Note=Localizesprimarilyatthecellsurface(Bysimilarity).IdentifiedbymassspectrometryinmelanosomefractionsfromstageItostageIV. TISSUESPECIFICITY:Expressedatvariablelevelsinmanyhumantissues. PTM:PhosphorylateduponDNAdamage,probablybyATMorATR. DISEASE:SwissProt:P11166#DefectsinSLC2A1arethecauseofautosomaldominantGLUT1deficiencysyndrome[MIM:606777].Thisdiseasecausesadefectinglucosetransportacrosstheblood-brainbarrier.Itischaracterizedbyinfantileseizures,delayeddevelopment,andacquiredmicrocephaly. SIMILARITY:SwissProt:P11166##Belongstothemajorfacilitatorsuperfamily.Sugartransporter(TC2.A.1.1)family.Glucosetransportersubfamily. |
| MolecularWeight | 46kDa |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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