Millipore/05-775 |抗Ha-Ras抗体，克隆MC57，兔单克隆/05-775/100µ；L
市场价：
¥0.00
美元价：
0.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | 05-775 |
| BrandFamily | Upstate |
| TradeName |
|
| Description | Anti-Ha-RasAntibody,cloneMC57,rabbitmonoclonal |
| ProductInformation | |
|---|---|
| Format | Purified |
| Presentation | 0.1MTris-glycine,pH7.4,0.15MNaCl,0.05%sodiumazidebeforetheadditionofglycerolto30% |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | 2yearsat-20°C |
| Applications | |
|---|---|
| Application | ThisAnti-Ha-RasAntibody,cloneMC57isvalidatedforuseinWBforthedetectionofHa-Ras. |
| KeyApplications |
|
| BIOLOGicalInformation | |
|---|---|
| Immunogen | GSTfusionproteincorrespondingtofulllengthhumanHa-Ras |
| Clone | MC57 |
| Host | Rabbit |
| Specificity | Ha-Ras;doesnotcrossreactwithCdc42,RhoorRac1 |
| Isotype | IgG |
| SpeciesReactivity |
|
| SpeciesReactivityNote | Predictedtocross-reactwithmouseandratbasedonsequencehomology. |
| AntibodyType | MonoclonalAntibody |
| EntrezGeneNumber | |
| GeneSymbol |
|
| PurificationMethod | ProteinAPurfied |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P01112#RasproteinsbindGDP/GTPandpossessintrinsicGTPaseactivity. SIZE:189aminoacids;21298Da SUBUNIT:InitsGTP-boundforminteractswithPLCE1.InteractswithTBC1D10C.InteractswithRGL3(Bysimilarity). SUBCELLULARLOCATION:Cellmembrane;Lipid-anchor;Cytoplasmicside.Golgiapparatusmembrane;Lipid-anchor.Note=ShuttlesbetweentheplasmamembraneandtheGolgiapparatus. PTM:PalmitoylatedbytheZDHHC9-GOLGA7complex.Acontinuouscycleofde-andre-palmitoylationregulatesrapidexchangebetweenplasmamembraneandGolgi. DISEASE:SwissProt:P01112#DefectsinHRASarethecauseofCostellosyndrome[MIM:218040];alsoknownasfaciocutaneoskeletalsyndrome.Costellosyndromeisarareconditioncharacterizedbyprenatallyincreasedgrowth,postnatalgrowthdeficiency,mentalretardation,distinctivefacialappearance,cardiovascularabnormalities(typicallypulmonicstenosis,hypertrophiccardiomyopathyand/oratrialtachycardia),tumorpredisposition,skinandmusculoskeletalabnormalities.&Mutationswhichchangepositions12,13or61activatethepotentialofc-rastotransformculturedcellsandareimplicatedinavarietyofhumantumors.&DefectsinHRASareacauseofbladdercancer[MIM:109800].&DefectsinHRASarealsothecauseoforalsquamouscellcarcinoma(OSCC). SIMILARITY:SwissProt:P01112##BelongstothesmallGTPasesuperfamily.Rasfamily. |
| MolecularWeight | ~21kDa |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
|---|
品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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