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Millipore/AB10512 | Anti-Caspase 6 (active form) Antibody/AB10512/100 µg

Millipore/AB10512 | Anti-Caspase 6 (active form) Antibody/AB10512/100 µg
市场价:
¥6780.00
美元价:
4068.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | |
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CatalogueNumber | AB10512 |
Replaces | 04-1045 |
Description | Anti-Caspase6(activeform)Antibody |
AlternateNames |
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BackgroundInformation | Caspasesareafamilyofcytosolicaspartate-specificcysteineproteasesinvolvedintheinitiationandexecutionofapoptosis.Caspase6isamajorapoptoticexecutioner(1,2).Itexistsasapro-domainproteinandiscleavedbycaspase-3intotwosubunits,an18kDaanda10kDasubunitthatdimerizetoformtheactiveenzyme(3).Caspase6cleavesamongmanydifferentintracellularproteins,nuclearlamins.Laminsplayasignificantroleinmaintainingtheintegrityofthecellmembrane,andtheircleavageresultsinsubsequentcellularbreakdownanddeath(4). |
ProductInformation | |
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Format | AffinityPurified |
Control |
|
Presentation | Purifiedrabbitpolyclonalinbuffercontaining0.1MTris-Glycine(pH7.4,150mMNaCl)with0.05%sodiumazide. |
StorageandShippingInformation | |
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StorageConditions | Stablefor1yearat2-8°Cfromdateofreceipt. |
BIOLOGicalInformation | |
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Immunogen | KLH-conjugatedlinearpeptidecorrespondingtotheC-terminusofthelargesubunitofratCaspase6. |
Epitope | C-terminusofthelargesubunitofCaspase6 |
Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
Host | Rabbit |
Specificity | TheantibodyrecognizesthelargesubunitofactiveCaspase6. |
SpeciesReactivity |
|
SpeciesReactivityNote | Demonstratedtoreactwithhumanandrat.Predictedtoreactwithbovine,feline,andchimpanzeebasedon100%sequencehomology. |
AntibodyType | PolyclonalAntibody |
EntrezGeneNumber | |
EntrezGeneSummary | Memberofthecysteine-asparticacidprotease(caspase)familythatplaysaterminalroleinapoptosis[RGD]. |
GeneSymbol |
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PurificationMethod | AffinityPurfied |
UniProtNumber | |
UniProtSummary | SEQUENCESIMILARITIES:BelongstothepeptidaseC14Afamily. |
MolecularWeight | ~18kDaObserved.UniProtKB/TrEMBLQ6AZ23listsaMWof31,574Daforthefulllengthproteinwhichisnormallycleavedintoalargeandsmallsubunit. |
PhysicochemicalInformation |
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Dimensions |
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MaterialsInformation |
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MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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