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当前位置: 首页 > 产品中心 > Functional_antibody > Millipore/MAB5504A4 | Anti-Vesicular Glutamate Transporter 2 Antibody, Alexa Fluor® 488 | MAB5504A4/MAB5504A4/100 µ
商品详细Millipore/MAB5504A4 | Anti-Vesicular Glutamate Transporter 2 Antibody, Alexa Fluor® 488 | MAB5504A4/MAB5504A4/100 µ
Millipore/MAB5504A4 | Anti-Vesicular Glutamate Transporter 2 Antibody, Alexa Fluor® 488 | MAB5504A4/MAB5504A4/100 µ
Millipore/MAB5504A4 | Anti-Vesicular Glutamate Transporter 2 Antibody, Alexa Fluor® 488 | MAB5504A4/MAB5504A4/100 µ
商品编号: MAB5504A4
品牌: 密理博
市场价: ¥8020.00
美元价: 4812.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberMAB5504A4
DescriptionAnti-VesicularGlutamateTransporter2Antibody,AlexaFluor®488|MAB5504A4
AlternateNames
  • Vesicularglutamatetransporter2
  • VGluT2
  • Differentiation-associatedBNPI
  • Differentiation-associatedNa(+)-dependentinorganicphosphatecotransporter
  • Solutecarrierfamily17member6
BackgroundInformationVesicularGlutamateTransporter2(VGLUT2)isasodiumdependentinorganicphosphatecotransporterthatisinvolvedinthecalciumdependentglutamatereleasefromastrocytes.Itisexpressedinonlyasubsetofneurons,localizedtosynapticvesicles,atsynapsesexhibitingclassicalexcitatoryfeatures.VGLUT2mRNAisfoundinbrainregionsthatlackVGLUT1,arelatedproteinalsodisplayingsodiumdependentinorganicphosphatecotransporteractivity.
ProductInformation
FormatAlexaFluor®488
Control
  • Adultmousebraintissue
PresentationPurifiedmousemonoclonalIgG1conjugatedtoAlexaFluor®488inPBSwith0.1%sodiumazideand15mg/mLBSA.
StorageandShippingInformation
StorageConditionsMaintainrefrigeratedat2-8°Cprotectedfromlightinundilutedaliquotsforupto6monthsfromdateofreceipt.
Applications
KeyApplications
  • Immunohistochemistry
BIOLOGicalInformation
ImmunogenRecombinantproteinfromratVGLUT2.
Clone8G9.2
HostMouse
IsotypeIgG1
SpeciesReactivity
  • Mouse
  • Rat
  • Human
SpeciesReactivityNoteDemonstratedtoreactwithMouseandRat.PredictedtoreactwithHumanbasedon100%sequencehomology.
AntibodyTypeMonoclonalAntibody
EntrezGeneNumber
EntrezGeneSummaryNa+-dependentinorganicphosphatecotransporter;involvedinCa2+-dependentglutamatereleasefromastrocytes[RGD].
GeneSymbol
  • Slc17a6
  • Dnpi
  • Vglut2
  • VGLUT2
PurificationMethodProteinAPurfied
UniProtNumber
UniProtSummaryFUNCTION:Mediatestheuptakeofglutamateintosynapticvesiclesatpresynapticnerveterminalsofexcitatoryneuralcells.Mayalsoplayaroleintheendocrineglutamatergicsystemofothertissuessuchaspinealglandandpancreas.Mayalsomediatethetransportofinorganicphosphate.

SUBCELLULARLOCATION:Cytoplasmicvesicle,secretoryvesicle,synapticvesiclemembrane.Membrane;Multi-passmembraneprotein(Potential).Celljunction,synapse,synaptosome.

TISSUESPECIFICITY:Expressedinbrain(atproteinlevel).Expressedinbrainstem,deepnuclei,septalnuclei,nucleiofthediagonalband,frontalcortex,hypothalamus,midbrain,parietalcortexandtemporalcortex.AlsoexpressedinpinealglandandisletsofLangerhans.

SIMILARITY:Belongstothemajorfacilitatorsuperfamily.Sodium/anioncotransporterfamily.VGLUTsubfamily.

SIZE:582aminoacids;64392Da
MolecularWeightTheunconjugatedparentantibody(Cat.No.MAB5504)hasanobservedmolecularweightat~56kDa.
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。