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Millipore/AB5066P | Anti-Norepinephrine Transporter Antibody/AB5066P/50 µg
Millipore/AB5066P | Anti-Norepinephrine Transporter Antibody/AB5066P/50 µg
市场价：
¥7800.00
美元价：
4680.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | AB5066P |
| BrandFamily | Chemicon® |
| TradeName |
|
| Description | Anti-NorepinephrineTransporterAntibody |
| AlternateNames |
|
| ProductInformation | |
|---|---|
| Format | AffinityPurified |
| Control |
|
| Presentation | AffinityPurifiedimmunoglobulin.LiquidinPBSwith0.1%BSA. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainfor1yearat-20°Cfromdateofshipment.Aliquottoavoidrepeatedfreezingandthawing.Formaximumrecoveryofproduct,centrifugetheoriginalvialafterthawingandpriortoremovingthecap. |
| Applications | |
|---|---|
| Application | ThisAnti-NorepinephrineTransporterAntibodyisvalidatedforuseinELISA,WBforthedetectionofNorepinephrineTransporter. |
| KeyApplications |
|
| ApplicationNotes | Westernblot:1-10μg/mL(Chemiluminescencetechnique):NETcanexistisatleasttwoforms,ahighlyglycosylated~80kDaformisthemostcommoninbrain,andalesslyglycosylated54kDaformisalsoseeninsomeregionsandtissues. ELISA:1:10,000-1:100,000(50-100ngimmunogenpeptide/well)Optimalworkingdilutionsmustbedeterminedbytheenduser. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | A22aminoacidpeptidesequencemappingtothe1stextracellulardomainofratNET. |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Rabbit |
| Specificity | SpecificforNorepinephrineTransporter(NET).NorepinephrineTransporterisa617aminoacidlongintegralmembraneproteinbelongingtotheSodium:NeurotransmitterSymporterfamily(Brussetal.1995;Melikianetal.1994;Pacholczyketal.1991)Theimmunogenpeptideshowsnosignificanthomologywithotherotherknownproteins. |
| SpeciesReactivity |
|
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | TheSLC6A2geneencodesanorepinephrine(noradrenaline)transporter,whichisresponsIBLeforreuptakeofnorepinephrineintopresynapticnerveterminalsandisaregulatorofnorepinephrinehomeostasis(Kimetal.,2006[PubMed17146058]).[suppliedbyOMIM] |
| GeneSymbol |
|
| PurificationMethod | ImmunoAffinityPurified |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P23975#Aminetransporter.Terminatestheactionofnoradrenalinebyitshighaffinitysodium-dependentreuptakeintopresynapticterminals. SIZE:617aminoacids;69332Da SUBUNIT:InteractswithPRKCABP. SUBCELLULARLOCATION:Membrane;Multi-passmembraneprotein. DISEASE:SwissProt:P23975#DefectsinSLC6A2areacauseoforthostaticintolerance(OI)[MIM:604715].OIisasyndromecharacterizedbylightheadedness,fatigue,alteredmentationandsyncope.Itisassociatedwithposturaltachycardia.Plasmanorepinephrineconcentrationisabnormallyhigh. SIMILARITY:SwissProt:P23975##Belongstothesodium:neurotransmittersymporter(SNF)family. MISCELLANEOUS:Thisproteinisthetargetofpsychomotorstimulantssuchasamphetaminesorcocaine. |
| MolecularWeight | 80&54kDa |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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