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Millipore/AB2234 | Anti-Norepinephrine Transporter Antibody/AB2234/100 µg
Millipore/AB2234 | Anti-Norepinephrine Transporter Antibody/AB2234/100 µg
市场价：
¥6980.00
美元价：
4188.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | AB2234 |
| Description | Anti-NorepinephrineTransporterAntibody |
| AlternateNames |
|
| BackgroundInformation | TheSLC6A2geneencodesanorepinephrine(noradrenaline)transporter,whichisresponsIBLeforreuptakeofnorepinephrineintopresynapticnerveterminalsandisaregulatorofnorepinephrinehomeostasis.Italsoappearstotransporttheneurotransmitterdopamineinthesameway,buttoalesserdegree.IntheCNS,norepinephrineisinvolvedinanumberofphysiologicalresponsesincludingmood,sleepregulation,alertnessandarousal,bothcognitiveandnon-cognitiveexpressionofbehaviors,andcontroloftheendocrineandautonomicnervoussystems.Peripherally,norepinephrineispresentinsympatheticnerveendingsandhasfullcontrolofthesympatheticnervoussystem.Certainantidepressantmedicationsacttoraisenorepinephrine,suchastheSNRIsandthetricyclicantidepressants(TCAs).Inessence,thesemedicationspreventthenorepinephrinetransporterfromservingitspurpose.Norepinephrinethereforeremainsinthesynapselonger,allowingittoreachmorenormallevels.Sincethenorepinephrinetransporterisalsothoughttotransportdopaminetosomeextent,SNRIswouldalsoraisedopaminelevelsinthesynapse. |
| ProductInformation | |
|---|---|
| Format | Purified |
| Control |
|
| Presentation | Purifiedin0.1MTris-Glycine(pH7.4)15mMNaClwith0.05%NaN3 |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainat2-8°Cinundilutedaliquotsforupto1yearafterdateofreceipt. |
| Applications | |
|---|---|
| Application | Anti-NorepinephrineTransporterAntibodydetectslevelofNorepinephrineTransporter&hasbeenpublished&validatedforuseinWB. |
| KeyApplications |
|
| BIOLOGicalInformation | |
|---|---|
| Immunogen | SyntheticLinearPeptide |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Rabbit |
| Specificity | Cat.#AB2234recognizesnorepinephrinetransporter |
| SpeciesReactivity |
|
| SpeciesReactivityNote | Rat.Mayreactwithhuman,mouse,dogandcowbasedonsequencehomology.Reactivitywithotherspecieshasnotbeendetermined. |
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | TheSLC6A2geneencodesanorepinephrine(noradrenaline)transporter,whichisresponsibleforreuptakeofnorepinephrineintopresynapticnerveterminalsandisaregulatorofnorepinephrinehomeostasis(Kimetal.,2006[PubMed17146058]).[suppliedbyOMIM] |
| GeneSymbol |
|
| PurificationMethod | ImmunoAffinityPurified |
| UniProtNumber | |
| UniProtSummary | LOCATION:Membrane;Multi-passmembraneprotein. SIMILARITY:Belongstothesodium:neurotransmittersymporter(SNF)family |
| MolecularWeight | ~69kDa |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
|---|
品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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