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Millipore/AB1585 | Anti-Dopamine β Hydroxylase Antibody/AB1585/50 µL
Millipore/AB1585 | Anti-Dopamine β Hydroxylase Antibody/AB1585/50 µL
市场价：
¥6780.00
美元价：
4068.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | AB1585 |
| Replaces | AB145 |
| BrandFamily | Chemicon® |
| TradeName |
|
| Description | Anti-DopamineβHydroxylaseAntibody |
| AlternateNames |
|
| ProductInformation | |
|---|---|
| Format | Serum |
| Control |
|
| Presentation | RabbitSerum.Lyophilized,nopreservatives.Reconstitutewith50μLofsteriledistilledwater.Centrifugetoremoveanyinsolublematerial. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainlyophilizedmaterialat-20to-70°Cforupto12monthsafterdateofreceipt.Afterreconstitutionmaintainat-20to-70°Cinundilutedaliquotsforuptosixmonths.Avoidrepeatedfreeze/thawcycles.Glycerolcanbeadded1:1foradditionalstABIlity. |
| Applications | |
|---|---|
| Application | DetectDopamineβHydroxylaseusingthisAnti-DopamineβHydroxylaseAntibodyvalidatedforuseinIH,FUNC,RIA&WB. |
| KeyApplications |
|
| ApplicationNotes | Immunohistochemistry:1:2,000onrabbitandguineapigusinganABCdetectionmethod. Westernblot RIA Inhibitorystudiesinvivoandinvitro. Optimalworkingdilutionsmustbedeterminedbytheenduser. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | Nativeenzymefrombovineadrenalglands. |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Rabbit |
| Specificity | RecognizesDopaminebetahydroxylase.AB1585reactswithasinglebandonWesternblotsofbovineadrenalhomogenatesandstainsonlycellsknowntocontainDBH,suchassympatheticneurons,adrenalmedullarycellsandcentraladrenergicneurons.Stainingisabolishedbypreincubationwithenzyme. |
| SpeciesReactivity |
|
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | TheproteinencodedbythisgeneisanoxidoreductasebelongingtothecoppertypeII,ascorbate-dependentmonooxygenasefamily.Itispresentinthesynapticvesiclesofpostganglionicsympatheticneuronsandconvertsdopaminetonorepinephrine.Itexistsinbothsolubleandmembrane-boundforms,dependingontheabsenceorpresence,respectively,ofasignalpeptide. |
| GeneSymbol |
|
| PurificationMethod | Unpurified |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P09172#Conversionofdopaminetonoradrenaline. COFACTOR:Binds1PQQpersubunit.&Binds2copperionspersubunit. SIZE:617aminoacids;69065Da SUBUNIT:Homotetramercomposedoftwonon-covalentlybounddisulfide-linkeddimers. SUBCELLULARLOCATION:Solubledopaminebeta-hydroxylase:Cytoplasmicvesicle,secretoryvesiclelumen.Cytoplasmicvesicle,secretoryvesicle,chromaffingranulelumen.&Cytoplasmicvesicle,secretoryvesiclemembrane;Single-passtypeIImembraneprotein.Cytoplasmicvesicle,secretoryvesicle,chromaffingranulemembrane;Single-passtypeIImembraneprotein(Potential). DISEASE:SwissProt:P09172#DefectsinDBHarethecauseofDBHdeficiency[MIM:223360];alsocallednorepinephrinedeficiencyornoradrenalinedeficiency.Thisdisorderischaracterizedbyprofounddeficitsinautonomicandcardiovascularfunction,butapparentlyonlysubtlesigns,ifany,ofcentralnervoussystemdysfunction. SIMILARITY:SwissProt:P09172##BelongstothecoppertypeIIascorbate-dependentmonooxygenasefamily.&Contains1DOMONdomain. |
| MolecularWeight | 69kDa |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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