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Millipore/AB1538 | Anti-Dopamine β Hydroxylase Antibody, NT/AB1538/100 µL
Millipore/AB1538 | Anti-Dopamine β Hydroxylase Antibody, NT/AB1538/100 µL
市场价:
¥6360.00
美元价:
3816.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | AB1538 |
| BrandFamily | Chemicon® |
| TradeName |
|
| Description | Anti-DopamineβHydroxylaseAntibody,NT |
| AlternateNames |
|
| ProductInformation | |
|---|---|
| Format | AffinityPurified |
| Presentation | Liquidin10mMHEPES(pH7.5),150mMNaCl,100μg/mLBSAand50%glycerol. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainat-20to-70°Cinundilutedaliquotsforuptosixmonths.Avoidrepeatedfreeze-thawcycles. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | Syntheticpeptide,CSAPRESPLPYHIPLDPEG-amide,clonedfromhuman(DbetaH)CDNA(Nagatsuetal.1990). |
| Epitope | N-terminus |
| Host | Rabbit |
| Specificity | DopamineBetaHydroxylase(DbetaH)N-terminal.Byimmunoblottheantibodyspecificallyreactswithasingle(ordouble)band(s)ofM.W.»70-75,000insamplesofSDS-solubilized,DTT-reducedhumanadrenalmedullasubjectedtoSDS-PAGE. |
| SpeciesReactivity |
|
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | TheproteinencodedbythisgeneisanoxidoreductasebelongingtothecoppertypeII,ascorbate-dependentmonooxygenasefamily.Itispresentinthesynapticvesiclesofpostganglionicsympatheticneuronsandconvertsdopaminetonorepinephrine.Itexistsinbothsolubleandmembrane-boundforms,dependingontheabsenceorpresence,respectively,ofasignalpeptide. |
| GeneSymbol |
|
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P09172#Conversionofdopaminetonoradrenaline. COFACTOR:Binds1PQQpersubunit.&Binds2copperionspersubunit. SIZE:617aminoacids;69065Da SUBUNIT:Homotetramercomposedoftwonon-covalentlybounddisulfide-linkeddimers. SUBCELLULARLOCATION:Solubledopaminebeta-hydroxylase:Cytoplasmicvesicle,secretoryvesiclelumen.Cytoplasmicvesicle,secretoryvesicle,chromaffingranulelumen.&Cytoplasmicvesicle,secretoryvesiclemembrane;Single-passtypeIImembraneprotein.Cytoplasmicvesicle,secretoryvesicle,chromaffingranulemembrane;Single-passtypeIImembraneprotein(Potential). DISEASE:SwissProt:P09172#DefectsinDBHarethecauseofDBHdeficiency[MIM:223360];alsocallednorepinephrinedeficiencyornoradrenalinedeficiency.Thisdisorderischaracterizedbyprofounddeficitsinautonomicandcardiovascularfunction,butapparentlyonlysubtlesigns,ifany,ofcentralnervoussystemdysfunction. SIMILARITY:SwissProt:P09172##BelongstothecoppertypeIIascorbate-dependentmonooxygenasefamily.&Contains1DOMONdomain. |
| PhysicochemicalInformation |
|---|
| Dimensions |
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| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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