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当前位置: 首页 > 产品中心 > Functional_antibody > 密理博/AB1537 |抗多巴胺β羟化酶抗体,CT/AB1537/100µ;L
商品详细密理博/AB1537 |抗多巴胺β羟化酶抗体,CT/AB1537/100µ;L
密理博/AB1537 |抗多巴胺β羟化酶抗体,CT/AB1537/100µ;L
密理博/AB1537 |抗多巴胺β羟化酶抗体,CT/AB1537/100µ;L
商品编号: AB1537
品牌: 密理博
市场价: ¥6580.00
美元价: 3948.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberAB1537
BrandFamilyChemicon®
TradeName
  • Chemicon
DescriptionAnti-DopamineβHydroxylaseAntibody,CT
AlternateNames
  • DBH
ProductInformation
FormatAffinityPurified
PresentationAffinitypurifiedimmunoglobulin.Liquidin10mMHEPES,pH7.5,150mMNaCl,100μg/mLBSAand50%glycerol.
StorageandShippingInformation
StorageConditionsMaintainat-20to-70°Cinundilutedaliquotsforuptosixmonths.Avoidrepeatedfreeze-thawcycles.
Applications
ApplicationThisAnti-DopamineβHydroxylaseAntibody,C-terminusisvalidatedforuseinWB,IHforthedetectionofDopamineβHydroxylase.
KeyApplications
  • WesternBlotting
  • Immunohistochemistry
ApplicationNotesImmunoblotting:1:250-1:1,000onhuman,monkeyandbovineadrenalmedulla.

Immunohistochemistry:1:250-1:1,000,stainingwasevaluatedinthelocuscoeruleusofformaldehyde-fixed,cryopreservedhumanandmonkeybrain.Showedstrongstainingonbothhumanandmonkey.

Optimalworkingdilutionsmustbedeterminedbytheenduser.
BIOLOGicalInformation
ImmunogenSyntheticpeptide,CPTSQGRSPAGPTVVSI-amide,fromC-terminalregionofhuman(DbetaH).
EpitopeC-terminus
HostSheep
SpecificityDopamineBetaHydroxylase(DbetaH)C-terminal.Byimmunoblottheantibodyspecificallyreactswithasingle(ordouble)band(s)ofM.W.»70-75,000insamplesofSDS-solubilized,DTT-reducedhumanadrenalmedullasubjectedtoSDS-PAGE.
SpeciesReactivity
  • Human
  • Monkey
AntibodyTypePolyclonalAntibody
EntrezGeneNumber
EntrezGeneSummaryTheproteinencodedbythisgeneisanoxidoreductasebelongingtothecoppertypeII,ascorbate-dependentmonooxygenasefamily.Itispresentinthesynapticvesiclesofpostganglionicsympatheticneuronsandconvertsdopaminetonorepinephrine.Itexistsinbothsolubleandmembrane-boundforms,dependingontheabsenceorpresence,respectively,ofasignalpeptide.
GeneSymbol
  • DBH
  • DBM
  • EC1.14.17.1[Contains:Solubledopaminebeta-hydroxylase].
UniProtNumber
UniProtSummaryFUNCTION:SwissProt:P09172#Conversionofdopaminetonoradrenaline.
COFACTOR:Binds1PQQpersubunit.&Binds2copperionspersubunit.
SIZE:617aminoacids;69065Da
SUBUNIT:Homotetramercomposedoftwonon-covalentlybounddisulfide-linkeddimers.
SUBCELLULARLOCATION:Solubledopaminebeta-hydroxylase:Cytoplasmicvesicle,secretoryvesiclelumen.Cytoplasmicvesicle,secretoryvesicle,chromaffingranulelumen.&Cytoplasmicvesicle,secretoryvesiclemembrane;Single-passtypeIImembraneprotein.Cytoplasmicvesicle,secretoryvesicle,chromaffingranulemembrane;Single-passtypeIImembraneprotein(Potential).
DISEASE:SwissProt:P09172#DefectsinDBHarethecauseofDBHdeficiency[MIM:223360];alsocallednorepinephrinedeficiencyornoradrenalinedeficiency.Thisdisorderischaracterizedbyprofounddeficitsinautonomicandcardiovascularfunction,butapparentlyonlysubtlesigns,ifany,ofcentralnervoussystemdysfunction.
SIMILARITY:SwissProt:P09172##BelongstothecoppertypeIIascorbate-dependentmonooxygenasefamily.&Contains1DOMONdomain.
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。