
密理博/AB1537 |抗多巴胺β羟化酶抗体,CT/AB1537/100µ;L
市场价:
¥6580.00
美元价:
3948.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | |
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CatalogueNumber | AB1537 |
BrandFamily | Chemicon® |
TradeName |
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Description | Anti-DopamineβHydroxylaseAntibody,CT |
AlternateNames |
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ProductInformation | |
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Format | AffinityPurified |
Presentation | Affinitypurifiedimmunoglobulin.Liquidin10mMHEPES,pH7.5,150mMNaCl,100μg/mLBSAand50%glycerol. |
StorageandShippingInformation | |
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StorageConditions | Maintainat-20to-70°Cinundilutedaliquotsforuptosixmonths.Avoidrepeatedfreeze-thawcycles. |
BIOLOGicalInformation | |
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Immunogen | Syntheticpeptide,CPTSQGRSPAGPTVVSI-amide,fromC-terminalregionofhuman(DbetaH). |
Epitope | C-terminus |
Host | Sheep |
Specificity | DopamineBetaHydroxylase(DbetaH)C-terminal.Byimmunoblottheantibodyspecificallyreactswithasingle(ordouble)band(s)ofM.W.»70-75,000insamplesofSDS-solubilized,DTT-reducedhumanadrenalmedullasubjectedtoSDS-PAGE. |
SpeciesReactivity |
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AntibodyType | PolyclonalAntibody |
EntrezGeneNumber | |
EntrezGeneSummary | TheproteinencodedbythisgeneisanoxidoreductasebelongingtothecoppertypeII,ascorbate-dependentmonooxygenasefamily.Itispresentinthesynapticvesiclesofpostganglionicsympatheticneuronsandconvertsdopaminetonorepinephrine.Itexistsinbothsolubleandmembrane-boundforms,dependingontheabsenceorpresence,respectively,ofasignalpeptide. |
GeneSymbol |
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UniProtNumber | |
UniProtSummary | FUNCTION:SwissProt:P09172#Conversionofdopaminetonoradrenaline. COFACTOR:Binds1PQQpersubunit.&Binds2copperionspersubunit. SIZE:617aminoacids;69065Da SUBUNIT:Homotetramercomposedoftwonon-covalentlybounddisulfide-linkeddimers. SUBCELLULARLOCATION:Solubledopaminebeta-hydroxylase:Cytoplasmicvesicle,secretoryvesiclelumen.Cytoplasmicvesicle,secretoryvesicle,chromaffingranulelumen.&Cytoplasmicvesicle,secretoryvesiclemembrane;Single-passtypeIImembraneprotein.Cytoplasmicvesicle,secretoryvesicle,chromaffingranulemembrane;Single-passtypeIImembraneprotein(Potential). DISEASE:SwissProt:P09172#DefectsinDBHarethecauseofDBHdeficiency[MIM:223360];alsocallednorepinephrinedeficiencyornoradrenalinedeficiency.Thisdisorderischaracterizedbyprofounddeficitsinautonomicandcardiovascularfunction,butapparentlyonlysubtlesigns,ifany,ofcentralnervoussystemdysfunction. SIMILARITY:SwissProt:P09172##BelongstothecoppertypeIIascorbate-dependentmonooxygenasefamily.&Contains1DOMONdomain. |
PhysicochemicalInformation |
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Dimensions |
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MaterialsInformation |
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MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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