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当前位置: 首页 > 产品中心 > Functional_antibody > Millipore/MAB5514 | Anti-Choline Transporter Antibody, clone 62-2E8/MAB5514/100 µL
商品详细Millipore/MAB5514 | Anti-Choline Transporter Antibody, clone 62-2E8/MAB5514/100 µL
Millipore/MAB5514 | Anti-Choline Transporter Antibody, clone 62-2E8/MAB5514/100 µL
Millipore/MAB5514 | Anti-Choline Transporter Antibody, clone 62-2E8/MAB5514/100 µL
商品编号: MAB5514
品牌: 密理博
市场价: ¥7600.00
美元价: 4560.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberMAB5514
BrandFamilyChemicon®
TradeName
  • Chemicon
DescriptionAnti-CholineTransporterAntibody,clone62-2E8
AlternateNames
  • CHT
ProductInformation
FormatAscites
PresentationAscitesfluid.Liquid.Containsnopreservative.
StorageandShippingInformation
StorageConditionsMaintainat-20°Cinundilutedaliquotsforupto12monthsafterdateofreceipt.Avoidrepeatedfreeze/thawcycles.
Applications
ApplicationDetectCholineTransporterusingthisAnti-CholineTransporterAntibody,clone62-2E8validatedforuseinIC,IH&WB.
KeyApplications
  • Immunocytochemistry
  • Immunohistochemistry
  • WesternBlotting
ApplicationNotesWesternblot.Theantibodydetectsa65kDabandinmousebraintissuelysate.TheCHTimmunoreactivitywasmostabundantinthestriatum.

Immunohistochemistry1:2,000-1:8,000

Immunocytochemistry

Optimalworkingdilutionsmustbedeterminedbyenduser.
BIOLOGicalInformation
ImmunogenRecombinantproteinfromtheC-terminusofhumanCHT.
Clone62-2E8
HostMouse
SpecificityHemicholinium-3-sensitivecholinetransporter(CHT).
IsotypeIgG1
SpeciesReactivity
  • Human
  • Mouse
AntibodyTypeMonoclonalAntibody
EntrezGeneNumber
EntrezGeneSummaryCholineisadirectprecursorofacetylcholine(ACh),aneurotransmitterofthecentralandperipheralnervoussystemthatregulatesavarietyofautonomic,cognitive,andmotorfunctions.SLC5A7isaNa(+)-andCl(-)-dependenthigh-affinitytransporterthatmediatestheuptakeofcholineforacetylcholinesynthesisincholinergicneurons(Apparsundarametal.,2000[PubMed11027560]).[suppliedbyOMIM]
GeneSymbol
  • SLC5A7
  • MGC126299
  • MGC126300
  • CHT1
  • hCHT
  • CHT
UniProtNumber
UniProtSummaryFUNCTION:SwissProt:Q9GZV3#Importscholinefromtheextracellularspacetotheneuronwithhighaffinity.Cholineuptakeistherate-limitingstepinacetylcholinesynthesis.Sodiumion-andchlorideion-dependent.
SIZE:580aminoacids;63204Da
SUBCELLULARLOCATION:Membrane;Multi-passmembraneprotein.
TISSUESPECIFICITY:Expressedinputamen,spinalcordandmedulla.Specificforcholinergicneurons.
PTM:Phosphorylated(Bysimilarity).
SIMILARITY:SwissProt:Q9GZV3##Belongstothesodium:solutesymporter(SSF)(TC2.A.21)family.
MISCELLANEOUS:Specificallyinhibitedbynanomolarconcentrationsofhemicholinium3.
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。