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当前位置: 首页 > 产品中心 > Functional_antibody > 密理博/AB5964 |抗胆碱乙酰转移酶抗体/AB5964/100µ;G
商品详细密理博/AB5964 |抗胆碱乙酰转移酶抗体/AB5964/100µ;G
密理博/AB5964 |抗胆碱乙酰转移酶抗体/AB5964/100µ;G
密理博/AB5964 |抗胆碱乙酰转移酶抗体/AB5964/100µ;G
商品编号: AB5964
品牌: 密理博
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberAB5964
BrandFamilyChemicon®
TradeName
  • Chemicon
DescriptionAnti-CholineAcetyltransferaseAntibody
AlternateNames
  • ChAT
ProductInformation
FormatAffinityPurified
PresentationAffinitypurifiedimmunoglobulin.Liquid.
StorageandShippingInformation
StorageConditionsMaintainat2-8°Cinundilutedaliquotsforupto6monthsafterdateofreceipt.

Duringshipment,smallvolumesofproductwilloccasionallybecomeentrappedinthesealoftheproductvial.Forproductswithvolumesof200μLorless,werecommendgentlytappingthevialonahardsurfaceorbrieflycentrifugingthevialinatabletopcentrifugetodislodgeanyliquidinthecontainer"scap.
Applications
ApplicationDetectCholineAcetyltransferaseusingthisAnti-CholineAcetyltransferaseAntibodyvalidatedforuseinIH&WB.
KeyApplications
  • Immunohistochemistry
  • WesternBlotting
ApplicationNotesImmunoblotting

Immunohistochemistry:1:200usingDABwithnickelenhancement.Theantibodyhasbeenusedsuccessfullyon50μmhumanmedullasectionswhichwereblockedwith3%H2O2for30min,blockedwith10%normalserum(donkey)for30minandcitratebuffer(pH3.0)retrievalfor30min.

Optimalworkingdilutionsmustbedeterminedbyenduser.
BIOLOGicalInformation
ImmunogenFusionprotein
HostRabbit
SpecificityCholineAcetyltransferase,human.Doesnotappeartoworkonratormouse.
SpeciesReactivity
  • Human
AntibodyTypePolyclonalAntibody
EntrezGeneNumber
EntrezGeneSummaryCholinergicsystemsareimplicatedinnumerousneurologicfunctions.AlterationinsomecholinergicneuronsmayaccountforthedisturbancesofAlzheimerdisease.Theproteinencodedbythisgenesynthesizestheneurotransmitteracetylcholine.Alternativesplicevariantshavebeenfoundthatcontainalternative5"untranslatedexons.Threeofthefourdescribedsplicevariantsencodeidentical69kDaproteinswhileonevariantencodesboththe69kDaandalarger82kDaprotein.
GeneSymbol
  • CHAT
  • ChAT
  • CMS1A2
  • CHOACTase
  • CMS1A
  • EC2.3.1.6
UniProtNumber
UniProtSummaryFUNCTION:SwissProt:P28329#CatalyzesthereversIBLesynthesisofacetylcholine(ACh)fromacetylCoAandcholineatcholinergicsynapses.
SIZE:748aminoacids;82568Da
DISEASE:SwissProt:P28329#DefectsinCHATarethecauseoffamilialinfantilemyastheniagravis2(FIMG2)[MIM:254210,254200];alsoknownasCMS-EA.FIMG2patientshavemyasthenicsymptomssincebirthorearlyinfancy,negativetestsforanti-AChRantibodies,andabruptepisodiccriseswithincreasedweakness,bulbarparalysis,andapneaprecipitatedbyundueexertion,fever,orexcitement.Inheritanceisautosomalrecessive.
SIMILARITY:SwissProt:P28329##Belongstothecarnitine/cholineacetyltransferasefamily.
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。