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Millipore/MAB5268 | Anti-Chromogranin A Antibody, clone LK2H10/MAB5268/500 µg500 μL
Millipore/MAB5268 | Anti-Chromogranin A Antibody, clone LK2H10/MAB5268/500 µg500 μL
市场价：
¥9240.00
美元价：
5544.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | MAB5268 |
| Replaces | CBL219 |
| BrandFamily | Chemicon® |
| TradeName |
|
| Description | Anti-ChromograninAAntibody,cloneLK2H10 |
| AlternateNames |
|
| BackgroundInformation | ChromograninA(aproteinof439aminoacidswhichisencodedonchromosome14)ispresentinneuroendocrinecellsthroughoutthebody,includingtheneuroendocrinecellsofthelargeandsmallintestine,adrenalmedullaandpancreaticislets.ItisanexcellentMarkerforcarcinoidtumors,phenochromocytomas,paragangliomas,andotherneuroendocrinetumors.CoexpressionofchromograninAandneuronspecificenolase(NSE)iscommoninneuroendocrineneoplasms. |
| ProductInformation | |
|---|---|
| Format | Purified |
| Control |
|
| Presentation | PurifiedmousemonoclonalIgG1inbuffercontaining0.05MBoratebufferedsaline,0.15MNaCl,pH8.2with0.1%sodiumazide. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Stablefor6monthsat2-8ºCinundilutedaliquotsfromdateofreceipt. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | Humanpheochromocytoma |
| Clone | LK2H10 |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Mouse |
| Specificity | Chromogranin,anacidicproteinhavingamolecularweightofabout68kDaABIdesinthepolypeptide-hormone-containingsecretorygranulesofhumanendocrinetissues.Anti-chromograninAcanbeusedtostainmostnormalandneoplasticendocrinetissuescontainingsecretorygranules(exceptionsincludecellsfromthehypothalamusandposteriorpituitary,whichareknowntocontainsecretorygranules).Theamountofstainingisusuallyproportionaltothenumberofsecretorygranulespresent(1). |
| Isotype | IgG1κ |
| SpeciesReactivity |
|
| SpeciesReactivityNote | Human,mouse,rat,monkey,andporcine.Doesnotrecognizesheep,rabbitorguineapig. |
| AntibodyType | MonoclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | Theproteinencodedbythisgeneisamemberofthechromogranin/secretograninfamilyofneuroendocrinesecretoryproteins.Itisfoundinsecretoryvesiclesofneuronsandendocrinecells.Thisgeneproductisaprecursortothreebiologicallyactivepeptides;vasostatin,pancreastatin,andparastatin.Thesepeptidesactasautocrineorparacrinenegativemodulatorsoftheneuroendocrinesystem.Otherpeptides,includingchromostatin,beta-granin,WE-14andGE-25,arealsoderivedfromthefull-lengthprotein.However,biologicalactivitiesforthesemoleculeshavenotbeenshown. |
| GeneSymbol |
|
| PurificationMethod | AmmoniumSulfatePrecipitation |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P10645#Pancreastatinstronglyinhibitsglucoseinducedinsulinreleasefromthepancreas. SIZE:457aminoacids;50730Da SUBCELLULARLOCATION:Secreted.Note=Neuroendocrineandendocrinesecretorygranules. PTM:Sulfatedontyrosineresiduesand/orcontainssulfatedglycans. SIMILARITY:SwissProt:P10645##Belongstothechromogranin/secretograninproteinfamily. MISCELLANEOUS:Bindscalciumwithalow-affinity |
| MolecularWeight | 50kDa |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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