当前位置:
首页
>
产品中心 >
Functional_antibody >
Millipore/MAB336 | Anti-Syntaxin Antibody, clone SP8/MAB336/100 µL

Millipore/MAB336 | Anti-Syntaxin Antibody, clone SP8/MAB336/100 µL
市场价:
¥5960.00
美元价:
3576.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | |
---|---|
CatalogueNumber | MAB336 |
BrandFamily | Chemicon® |
TradeName |
|
Description | Anti-SyntaxinAntibody,cloneSP8 |
AlternateNames |
|
ProductInformation | |
---|---|
Format | Ascites |
Presentation | Liquidwith0.1%SodiumAzide. |
StorageandShippingInformation | |
---|---|
StorageConditions | Maintainfrozenat-20°Cinundilutedaliquotsforupto12months.Avoidrepeatedfreeze/thawcycles. |
Applications | |
---|---|
Application | ThisAnti-SyntaxinAntibody,cloneSP8isvalidatedforuseinELISA,WB,IHforthedetectionofSyntaxin. |
KeyApplications |
|
ApplicationNotes | Immunohistochemistryat>1:100-1:200. Formalinfixed(fixed<4 weeks)="">4> Westernblottingat1:100-1:10,000. ELISAat1:500 Optimalworkingdilutionsmustbedeterminedbytheenduser. |
BIOLOGicalInformation | |
---|---|
Immunogen | Crudesynapticimmunoprecipitate(Human). |
Clone | SP8 |
Host | Mouse |
Specificity | Syntaxin(34-36kDa).Reactswithsyntaxinexpressedinbacterialsystems. |
Isotype | IgG1 |
SpeciesReactivity |
|
AntibodyType | MonoclonalAntibody |
EntrezGeneNumber | |
EntrezGeneSummary | Synapticvesiclesstoreneurotransmittersthatarereleasedduringcalcium-regulatedexocytosis.Thespecificityofneurotransmitterreleaserequiresthelocalizationofbothsynapticvesiclesandcalciumchannelstothepresynapticactivezone.Syntaxinsfunctioninthisvesiclefusionprocess.SyntaxinsalsoserveasasubstrateforbotulinumneurotoxintypeC,ametalloproteasethatblocksexocytosisandhashighaffinityforamolecularcomplexthatincludesthealpha-latrotoxinreceptor(MIM600565)whichproducesexplosiveexocytosis(Zhangetal.,1995[PubMed7622072]).[suppliedbyOMIM] |
GeneSymbol |
|
UniProtNumber | |
UniProtSummary | FUNCTION:SwissProt:Q16623#Potentiallyinvolvedindockingofsynapticvesiclesatpresynapticactivezones.Mayplayacriticalroleinneurotransmitterexocytosis. SIZE:288aminoacids;33023Da SUBUNIT:PartoftheSNAREcorecomplexcontainingSNAP25,VAMP2andSTX1A.ThiscomplexbindstoCPLX1.BindsSYTL4andSTXBP6.FoundinaternarycomplexwithSTX1AandSNAP25(Bysimilarity).FoundinacomplexwithVAMP8andSNAP23.InteractswithVAPAandSYBU. SUBCELLULARLOCATION:Cellmembrane;Single-passtypeIVmembraneprotein.&Isoform2:Secreted(Probable). TISSUESPECIFICITY:Isoform1ishighlyexpressedinembryonicspinalchordandgangliaandinadultcerebellumandcerebralcortex.Isoform2isexpressedinheart,liver,fat,skeletalmuscle,kidneyandbrain. DISEASE:SwissProt:Q16623#HaploinsufficiencyofSTX1Amaybethecauseofcertaincardiovascularandmusculo-skeletalabnormalitiesobservedinWilliams-Beurensyndrome(WBS),araredevelopmentaldisorder.Itisacontiguousgenedeletionsyndromeinvolvinggenesfromchromosomeband7q11.23. SIMILARITY:SwissProt:Q16623##Belongstothesyntaxinfamily.&Contains1t-SNAREcoiled-coilhomologydomain. |
PhysicochemicalInformation |
---|
Dimensions |
---|
MaterialsInformation |
---|
MaterialsInformation |
---|
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
联络我们