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Millipore/MAB331 | Anti-SNAP-25 Antibody, clone SP14/MAB331/100 µL
Millipore/MAB331 | Anti-SNAP-25 Antibody, clone SP14/MAB331/100 µL
市场价：
¥6160.00
美元价：
3696.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | MAB331 |
| BrandFamily | Chemicon® |
| TradeName |
|
| Description | Anti-SNAP-25Antibody,cloneSP14 |
| ProductInformation | |
|---|---|
| Format | Ascites |
| Presentation | Liquid.Containsnopreservative. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainfrozenat-20°Cinundilutedaliquotsforupto12months.Avoidrepeatedfreeze/thawcycles. |
| Applications | |
|---|---|
| Application | DetectSNAP-25usingthisAnti-SNAP-25Antibody,cloneSP14validatedforuseinELISA,WB,IH(P). |
| KeyApplications |
|
| ApplicationNotes | Immunohistochemistryat1:500-1:5,000 Formalinfixed(<4=""weeks),=""paraffin=""embedded=""> *ItissuggestedthatyouuseanIgGspecificsecondantibodytominimizepossIBLenon-specificstaining. Frozen Westernblottingat1:100-1:1,000 ELISAat1:500 ItisreportedthatcloneSP14iscapableofdetectingSDS-resistantSNAREcomplexes{J.CellSci2004117(6):955-966}. Optimalworkingdilutionsmustbedeterminedbytheenduser. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | Crudesynapticimmunoprecipitate(Human) |
| Clone | SP14 |
| Host | Mouse |
| Specificity | SNAP-25(26-27kDa).MAB331isreactivewithfusionproteinfromCOScells,butnotwithfusionproteinfrombacterialsystems. |
| Isotype | IgG1 |
| SpeciesReactivity |
|
| AntibodyType | MonoclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | SynapticvesiclemembranedockingandfusionismediatedbySNAREs(solubleN-ethylmaleimide-sensitivefactorattachmentproteinreceptors)locatedonthevesiclemembrane(v-SNAREs)andthetargetmembrane(t-SNAREs).Theassembledv-SNARE/t-SNAREcomplexconsistsofabundleoffourhelices,oneofwhichissuppliedbyv-SNAREandtheotherthreebyt-SNARE.Fort-SNAREsontheplasmamembrane,theproteinsyntaxinsuppliesonehelixandtheproteinencodedbythisgenecontributestheothertwo.Therefore,thisgeneproductisapresynapticplasmamembraneproteininvolvedintheregulationofneurotransmitterrelease.Twoalternativetranscriptvariantsencodingdifferentproteinisoformshavebeendescribedforthisgene. |
| GeneSymbol |
|
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P60880#t-SNAREinvolvedinthemolecularregulationofneurotransmitterrelease.Mayplayanimportantroleinthesynapticfunctionofspecificneuronalsystems.Associateswithproteinsinvolvedinvesicledockingandmembranefusion. SIZE:206aminoacids;23315Da SUBUNIT:PartoftheSNAREcorecomplexcontainingSNAP25,VAMP2andSTX1A.ThiscomplexbindsCPLX1.InteractswithTRIM9,RIMS1,SNAP25BPandHGS.BindsSTXBP6.FoundinaternarycomplexwithSTX1AandVAMP8.FoundinacomplexcontainingSYT1,SV2Bandsyntaxin-1(Bysimilarity). TISSUESPECIFICITY:Neuronsoftheneocortex,hippocampus,piriformcortex,anteriorthalamicnuclei,pontinenuclei,andgranulecellsofthecerebellum. PTM:Palmitoylated(Bysimilarity). SIMILARITY:SwissProt:P60880##BelongstotheSNAP-25family.&Contains2t-SNAREcoiled-coilhomologydomains. |
| PhysicochemicalInformation |
|---|
| Dimensions |
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| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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