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当前位置: 首页 > 产品中心 > Functional_antibody > Millipore/MAB319 | Anti-Chromogranin A Antibody, clone PHE5/MAB319/100 µL
商品详细Millipore/MAB319 | Anti-Chromogranin A Antibody, clone PHE5/MAB319/100 µL
Millipore/MAB319 | Anti-Chromogranin A Antibody, clone PHE5/MAB319/100 µL
Millipore/MAB319 | Anti-Chromogranin A Antibody, clone PHE5/MAB319/100 µL
商品编号: MAB319
品牌: 密理博
市场价: ¥5960.00
美元价: 3576.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberMAB319
BrandFamilyChemicon®
TradeName
  • Chemicon
DescriptionAnti-ChromograninAAntibody,clonePHE5
AlternateNames
  • CgA
  • PituitarySecretoryProteinI
ProductInformation
FormatPurified
Control
  • POSOTIVECONTROL:Normaladrenalgland,bowel,orthyroidtissue.
PresentationLiquidin0.02MPhosphatebuffer,0.25MNaCl,pH7.6with0.1%sodiumazide.
StorageandShippingInformation
StorageConditionsMaintainat2-8°Cinundilutedaliquotsforupto6monthsfromdateofreceipt.
Applications
ApplicationAnti-ChromograninAAntibody,clonePHE5detectslevelofChromograninA&hasbeenpublished&validatedforuseinWB,IH(P).
KeyApplications
  • WesternBlotting
  • Immunohistochemistry(Paraffin)
ApplicationNotesImmunohistochemistry:1:500-1:2,000onalcoholfixeddeparaffinizedtissuesections(ABCperoxidase)or1:10,000onMethacarn-fixeddeparaffinizedtissuesections.Willshowfinegranularcytoplasmicstainingassociatedwithsecretorygranules.

WesternBlot:recognizesabandmigratingatapproximately68-75kDacorrespondingtochromograninA.

Optimalworkingdilutionsmustbedeterminedbytheenduser.
BIOLOGicalInformation
ImmunogenHumanpheochromocytoma
ClonePHE5
ConcentrationPleaserefertotheCertificateofAnalysisforthelot-specificconcentration.
HostMouse
SpecificityChromograninA.Theantibodyhasbeenextensivelydocumentedonimmunohistochemicalstudiesindeparaffinizedmethacarnfixedtissue,whereitisasensitiveMarkerofneuroendocrinecellsandtumors.Notrecommendedforformalinfixedtissues,seeMAB5268orCBL219.Onwesternblots,itidentifiestheidenticalbandsrecognizedbyantibodyLK2H10(WilsonandLloyd).
IsotypeIgG1
SpeciesReactivity
  • Human
  • Monkey
AntibodyTypeMonoclonalAntibody
EntrezGeneNumber
EntrezGeneSummaryTheproteinencodedbythisgeneisamemberofthechromogranin/secretograninfamilyofneuroendocrinesecretoryproteins.Itisfoundinsecretoryvesiclesofneuronsandendocrinecells.Thisgeneproductisaprecursortothreebiologicallyactivepeptides;vasostatin,pancreastatin,andparastatin.Thesepeptidesactasautocrineorparacrinenegativemodulatorsoftheneuroendocrinesystem.Otherpeptides,includingchromostatin,beta-granin,WE-14andGE-25,arealsoderivedfromthefull-lengthprotein.However,biologicalactivitiesforthesemoleculeshavenotbeenshown.
GeneSymbol
  • CHGA
  • CgA
  • SP-I
  • CGA
Non-ReactiveSpecies
  • Mouse
  • Rat
UniProtNumber
UniProtSummaryFUNCTION:SwissProt:P10645#Pancreastatinstronglyinhibitsglucoseinducedinsulinreleasefromthepancreas.
SIZE:457aminoacids;50730Da
SUBCELLULARLOCATION:Secreted.Note=Neuroendocrineandendocrinesecretorygranules.
PTM:Sulfatedontyrosineresiduesand/orcontainssulfatedglycans.
SIMILARITY:SwissProt:P10645##Belongstothechromogranin/secretograninproteinfamily.
MISCELLANEOUS:Bindscalciumwithalow-affinity.
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。