Millipore/MAB303 |抗乙酰胆碱酯酶抗体，克隆AE-1/MAB303/100µ；G
市场价：
¥5120.00
美元价：
3072.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | MAB303 |
| BrandFamily | Chemicon® |
| TradeName |
|
| Description | Anti-AcetylcholinesteraseAntibody,cloneAE-1 |
| ProductInformation | |
|---|---|
| Format | Purified |
| Presentation | Liquidin0.02MPB,0.25MNaCl,pH7.6,with0.1%sodiumazide. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainat2-8°Cforupto6months. |
| Applications | |
|---|---|
| Application | ThisAnti-AcetylcholinesteraseAntibody,cloneAE-1isvalidatedforuseinELISA,IH,IPforthedetectionofAcetylcholinesterase. |
| KeyApplications |
|
| ApplicationNotes | ELISA Immunohistochemistry WesternBlot Optimalworkingdilutionsmustbedeterminedbyenduser. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | AcetylcholinesteraseAChEfromhumanerythrocyte. |
| Clone | AE-1 |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Mouse |
| Specificity | Acetylcholinesterasefromhumanandmonkey. |
| Isotype | IgG1 |
| SpeciesReactivity |
|
| AntibodyType | MonoclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | Acetylcholinesterasehydrolyzestheneurotransmitter,acetylcholineatneuromuscularjunctionsandbraincholinergicsynapses,andthusterminatessignaltransmission.Itisalsofoundontheredbloodcellmembranes,whereitconstitutestheYtbloodgroupantigen.Acetylcholinesteraseexistsinmultiplemolecularformswhichpossesssimilarcatalyticproperties,butdifferintheiroligomericassemblyandmodeofcellattachmenttothecellsurface.ItisencodedbythesingleACHEgene,andthestructuraldiversityinthegeneproductsarisesfromalternativemRNAsplicing,andpost-translationalassociationsofcatalyticandstructuralsubunits.Themajorformofacetylcholinesterasefoundinbrain,muscleandothertissuesisthehydrophilicspecies,whichformsdisulfide-linkedoligomerswithcollagenous,orlipid-containingstructuralsubunits.Theother,alternativelysplicedform,expressedprimarilyintheerythroidtissues,differsattheC-terminalend,andcontainsacleavablehydrophobicpeptidewithaGPI-anchorsite.Itassociateswiththemembranesthroughthephosphoinositide(PI)moietiesaddedpost-translationally. |
| GeneSymbol |
|
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P22303#Rapidlyhydrolyzescholinereleasedintothesynapse. SIZE:614aminoacids;67796Da SUBUNIT:Homotetramer;composedofdisulfide-linkedhomodimers.InteractswithPRIMA1.TheinteractionwithPRIMA1isrequiredtoanchorittothebasallaminaofcellsandorganizeintotetramers(Bysimilarity). SUBCELLULARLOCATION:Celljunction,synapse.Secreted(Bysimilarity).Cellmembrane;Peripheralmembraneprotein(Bysimilarity).&Isoform2:Cellmembrane;Lipid-anchor,GPI-anchor;Extracellularside(Bysimilarity). SIMILARITY:SwissProt:P22303##Belongstothetype-Bcarboxylesterase/lipasefamily. |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
|---|
品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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