Millipore/AB9876 | Anti-Stargazin Antibody/AB9876/100 µg
市场价：
¥7180.00
美元价：
4308.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | AB9876 |
| BrandFamily | Chemicon® |
| TradeName |
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| Description | Anti-StargazinAntibody |
| AlternateNames |
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| ProductInformation | |
|---|---|
| Format | Purified |
| Presentation | Liquidin130mMTris-Cl,87mMGlycine,pH7.4. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainat-80°Cinundilutedaliquotsforupto6monthsafterdateofreceipt.Avoidrepeatedfreezethawcycles.Theantibodymaybekeptat2-8°Cfor1-3weeksafterthawing. |
| Applications | |
|---|---|
| Application | ThisAnti-StargazinAntibodyisvalidatedforuseinIP,WB,IC,IHforthedetectionofStargazin. |
| KeyApplications |
|
| ApplicationNotes | Westernblot:0.1μg/mLonTritonsolublefractionofratbrain.SuggesteddilutionbufferisTBS-Tandblockingbufferis3%skimmilk.Suggestedincubationtimeis3hourstoovernightatroomtemperature. Immunohistochemistry:0.25-0.5μg/mLon4%paraformaldehydefixedtissue.SuggesteddilutionbufferisPBS-T.SuggestedpermeABIlizationmethodis0.1%TritonX-100.Suggestedincubationtimeis2hourstoovernightatroomtemperature. Immunocytochemistry Immunoprecipitation:1-2μg.Suggestedreactionvolumeis200-1000μL.Suggestedtotalproteinconcentrationis2mg/mL.Suggestedincubationtimeis2hoursat2-8°C.SuggestedcaptureagentisProteinA. Optimalworkingdilutionsmustbedeterminedbyenduser. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | GSTfusionproteinfromratstargazin,cytoplasmicdomain. |
| Host | Rabbit |
| Specificity | Stargazin[Stargazin-likeTARP(transmembraneAMPAreceptorregulatoryprotein)].ByWesternblottheantibodyrecognizesbandsat~35kDaand~55kDaonTritonsolublefractionofratbrain.TheantibodyreactsdominantlywithTARPgamma-8andweaklywithgamma-3andgamma-4.Stargazinisexpressedstronglyinthehippocampusandcerebellum. |
| SpeciesReactivity |
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| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | L-typecalciumchannelsarecomposedoffivesubunits.Theproteinencodedbythisgenerepresentsoneofthesesubunits,gamma,andisoneofseveralgammasubunitproteins.Itisanintegralmembraneproteinthatisthoughttostabilizethecalciumchannelinaninactive(closed)state.Thisproteinissimilartothemousestargazinprotein,mutationsinwhichhavebeenassociatedwithabsenceseizures,alsoknownaspetit-malorspike-waveseizures.ThisgeneisamemberoftheneuronalcalciumchannelgammasubunitgenesubfamilyofthePMP-22/EMP/MP20family. |
| GeneSymbol |
|
| PurificationMethod | ImmunoAffinityPurified |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:Q9Y698#Thoughttostabilizethecalciumchannelinaninactivated(closed)state. SIZE:323aminoacids;35966Da SUBUNIT:TheL-typecalciumchanneliscomposedoffivesubunits:alpha-1,alpha-2/delta,betaandgamma.InteractswiththePDZdomainsofDLG4/PSD-95andDLG1/SAP97.MayinteractwithGOPC(Bysimilarity). SUBCELLULARLOCATION:Membrane;Multi-passmembraneprotein. TISSUESPECIFICITY:Brain. PTM:PhosphorylationofThr-321impairsinteractionwithDLG1andDLG4. SIMILARITY:SwissProt:Q9Y698##BelongstothePMP-22/EMP/MP20family.CACNGsubfamily. |
| PhysicochemicalInformation |
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| Dimensions |
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| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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