
Millipore/AB5871 | Anti-SNAP-25 Antibody/AB5871/50 µL
市场价:
¥5120.00
美元价:
3072.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | |
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CatalogueNumber | AB5871 |
BrandFamily | Chemicon® |
TradeName |
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Description | Anti-SNAP-25Antibody |
AlternateNames |
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ProductInformation | |
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Format | Purified |
Presentation | IgGfraction(proteinA)inPBSwith50%Glyceroland0.01%sodiumazide. |
StorageandShippingInformation | |
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StorageConditions | Maintainat-20°Cinundilutedforupto6monthsfromdateofreceipt.Avoidrepeatedfreeze/thawcycles. |
Applications | |
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Application | Anti-SNAP-25AntibodyisanantibodyagainstSNAP-25foruseinIP,WB,IH. |
KeyApplications |
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ApplicationNotes | Westernblot:1:100-1:2000 ELISA:1:1000-1:100,000 Immunohistochemistry:1:50-1:100 Optimalworkingdilutionsmustbedeterminedbytheenduser. |
BIOLOGicalInformation | |
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Immunogen | RecombinanthumanSNAP-25 |
Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
Host | Goat |
Specificity | SNAP-25 |
SpeciesReactivity |
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AntibodyType | PolyclonalAntibody |
EntrezGeneNumber | |
EntrezGeneSummary | SynapticvesiclemembranedockingandfusionismediatedbySNAREs(solubleN-ethylmaleimide-sensitivefactorattachmentproteinreceptors)locatedonthevesiclemembrane(v-SNAREs)andthetargetmembrane(t-SNAREs).Theassembledv-SNARE/t-SNAREcomplexconsistsofabundleoffourhelices,oneofwhichissuppliedbyv-SNAREandtheotherthreebyt-SNARE.Fort-SNAREsontheplasmamembrane,theproteinsyntaxinsuppliesonehelixandtheproteinencodedbythisgenecontributestheothertwo.Therefore,thisgeneproductisapresynapticplasmamembraneproteininvolvedintheregulationofneurotransmitterrelease.Twoalternativetranscriptvariantsencodingdifferentproteinisoformshavebeendescribedforthisgene. |
GeneSymbol |
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UniProtNumber | |
UniProtSummary | FUNCTION:SwissProt:P60880#t-SNAREinvolvedinthemolecularregulationofneurotransmitterrelease.Mayplayanimportantroleinthesynapticfunctionofspecificneuronalsystems.Associateswithproteinsinvolvedinvesicledockingandmembranefusion. SIZE:206aminoacids;23315Da SUBUNIT:PartoftheSNAREcorecomplexcontainingSNAP25,VAMP2andSTX1A.ThiscomplexbindsCPLX1.InteractswithTRIM9,RIMS1,SNAP25BPandHGS.BindsSTXBP6.FoundinaternarycomplexwithSTX1AandVAMP8.FoundinacomplexcontainingSYT1,SV2Bandsyntaxin-1(Bysimilarity). TISSUESPECIFICITY:Neuronsoftheneocortex,hippocampus,piriformcortex,anteriorthalamicnuclei,pontinenuclei,andgranulecellsofthecerebellum. PTM:Palmitoylated(Bysimilarity). SIMILARITY:SwissProt:P60880##BelongstotheSNAP-25family.&Contains2t-SNAREcoiled-coilhomologydomains. |
PhysicochemicalInformation |
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Dimensions |
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MaterialsInformation |
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MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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