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当前位置: 首页 > 产品中心 > Functional_antibody > Millipore/AB5856-50UL | Anti-VAMP-2 Antibody/AB5856-50UL/50 µL
商品详细Millipore/AB5856-50UL | Anti-VAMP-2 Antibody/AB5856-50UL/50 µL
Millipore/AB5856-50UL | Anti-VAMP-2 Antibody/AB5856-50UL/50 µL
Millipore/AB5856-50UL | Anti-VAMP-2 Antibody/AB5856-50UL/50 µL
商品编号: AB5856-50UL
品牌: 密理博
市场价: ¥6780.00
美元价: 4068.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberAB5856-50UL
BrandFamilyChemicon®
TradeName
  • Chemicon
DescriptionAnti-VAMP-2Antibody
AlternateNames
  • Vesicle-AssociatedMembraneProtein2
  • Synaptobrevin2
ProductInformation
FormatAffinityPurified
Control
  • CONTROLANTIGEN:Includedfreeofchargewiththeantibodyis50μgofcontrolantigen(lyophilizedpowder).Thestocksolutionoftheantigencanbemadeupusing100μLofPBS.Forpositivecontrol,inWesternblotusing20ngofproteinperMinigellane.Fornegativecontrol,preincubate3μgoffusionproteinwith1μgofantibodyforonehouratroomtemperature.Optimalconcentrationsmustbedeterminedbytheenduser.
PresentationAffinitypurifiedimmunoglobulin.Lyophilizedfromphosphatebufferedsaline,pH7.4,containing1%BSA,5%sucroseasastABIlizerand0.025%sodiumazideasapreservative.Reconstitutewith50μLofsteriledeionizedwater.Centrifugeantibodypreparationbeforeuse(10,000xgfor5min)
StorageandShippingInformation
StorageConditionsMaintainlyophilizedmaterialat-20°Cforupto12months.Afterreconstitutionmaintainat-20°Cinundilutedaliquotsforupto6months.Avoidrepeatedfreeze/thawcycles.
Applications
ApplicationAnti-VAMP-2AntibodydetectslevelofVAMP-2&hasbeenpublished&validatedforuseinWB.
KeyApplications
  • WesternBlotting
ApplicationNotesWesternblot:1:1,000usingECLonratbrainmembranes.

DilutionsshouldbemadeusingacarrierproteinsuchasBSA(1-3%)

Optimalworkingdilutionsmustbedeterminedbytheenduser.
BIOLOGicalInformation
ImmunogenGSTfusionproteincorrespondingtoacytoplasmic,N-terminalpartofratormouseVAMP-2(AccessionnumbersQ64357,NP036795).
ConcentrationPleaserefertotheCertificateofAnalysisforthelot-specificconcentration.
HostRabbit
SpecificityRecognizesVAMP-2(Vesicle-AssociatedMembraneProtein2,Synaptobrevin2).Theepitopedoesnotsharehomologywithanyotherknownproteins.

SPECIESREACTIVITIES:Itisexpectedthattheantibodywillalsoreactwithhuman,Macacamultataandbovineduetosequencehomology(25/26).Otherspecieshavenotbeentested.
SpeciesReactivity
  • Mouse
  • Rat
AntibodyTypePolyclonalAntibody
EntrezGeneNumber
EntrezGeneSummaryTheproteinencodedbythisgeneisamemberofthevesicle-associatedmembraneprotein(VAMP)/synaptobrevinfamily.Synaptobrevins/VAMPs,syntaxins,andthe25-kDsynaptosomal-associatedproteinSNAP25arethemaincomponentsofaproteincomplexinvolvedinthedockingand/orfusionofsynapticvesicleswiththepresynapticmembrane.Thisgeneisthoughttoparticipateinneurotransmitterreleaseatastepbetweendockingandfusion.Theproteinformsastablecomplexwithsyntaxin,synaptosomal-associatedprotein,25kD,andsynaptotagmin.Italsoformsadistinctcomplexwithsynaptophysin.Itisalikelycandidategeneforfamilialinfantilemyasthenia(FIMG)becauseofitsmaplocationandbecauseitencodesasynapticvesicleproteinofthetypethathasbeenimplicatedinthepathogenesisofFIMG.
GeneSymbol
  • VAMP2
  • VAMP-2
  • FLJ11460
  • Synaptobrevin-2
  • SYB2
UniProtNumber
UniProtSummaryFUNCTION:SwissProt:P63027#Involvedinthetargetingand/orfusionoftransportvesiclestotheirtargetmembrane.
SIZE:116aminoacids;12649Da
SUBUNIT:InteractswithVAPAandVAPB.
SUBCELLULARLOCATION:Cytoplasmicvesicle,secretoryvesicle,synapticvesiclemembrane;Single-passtypeIVmembraneprotein.Note=Neuronalsynapticvesicles.
TISSUESPECIFICITY:Nervoussystemandskeletalmuscle.
SIMILARITY:SwissProt:P63027##Belongstothesynaptobrevinfamily.&Contains1v-SNAREcoiled-coilhomologydomain.
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。