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Millipore/AB5600-50UL | Anti-Synaptotagmin I Antibody, luminal part/AB5600-50UL/50 µL
Millipore/AB5600-50UL | Anti-Synaptotagmin I Antibody, luminal part/AB5600-50UL/50 µL
商品编号：
AB5600-50UL
品牌：
密理博
市场价：
¥6160.00
美元价：
3696.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | AB5600-50UL |
| BrandFamily | Chemicon® |
| TradeName |
|
| Description | Anti-SynaptotagminIAntibody,luminalpart |
| AlternateNames |
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| ProductInformation | |
|---|---|
| Format | AffinityPurified |
| Control |
|
| Presentation | Affinitypurifiedimmunoglobulin.Lyophilizedfromphosphatebufferedsaline,pH7.4,containing1%BSA,5%sucroseasastABIlizerand0.025%sodiumazideasapreservative.Reconstitutewith50μLofsteriledeionizedwater.Centrifugeantibodypreparationbeforeuse(10,000xgfor5min). |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainlyophilizedmaterialat-20°Cforupto12months.Afterreconstitutionmaintainat-20°Cinundilutedaliquotsforupto6months.Avoidrepeatedfreeze/thawcycles. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | Peptidecorrespondingtoaminoacids1-19fromratSynaptotagminI(Accession#P21107). |
| Epitope | luminalpart |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Rabbit |
| Specificity | RecognizesSynaptotagminI,luminalpart.Theepitopedoesnotsharehomologywithanyotherknownproteins. SPECIESREACTIVITIES:Itisexpectedthattheantibodywillalsorecognizehuman.Otherspecieshavenotbeentested. |
| SpeciesReactivity |
|
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | ThesynaptotagminsareintegralmembraneproteinsofsynapticvesiclesthoughttoserveasCa(2+)sensorsintheprocessofvesiculartraffickingandexocytosis.CalciumbindingtosynaptotagminIparticipatesintriggeringneurotransmitterreleaseatthesynapse(Fernandez-Chaconetal.,2001[PubMed11242035]).[suppliedbyOMIM] |
| GeneSymbol |
|
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P21579#Mayhavearegulatoryroleinthemembraneinteractionsduringtraffickingofsynapticvesiclesattheactivezoneofthesynapse.Itbindsacidicphospholipidswithaspecificitythatrequiresthepresenceofbothanacidicheadgroupandadiacylbackbone.ACa(2+)-dependentinteractionbetweensynaptotagminandputativereceptorsforactivatedproteinkinaseChasalsobeenreported.ItcanbindtoatleastthreeadditionalproteinsinaCa(2+)-independentmanner;theseareneurexins,syntaxinandAP2. COFACTOR:Binds3calciumionspersubunit.TheionsareboundtotheC2domains(Bysimilarity). SIZE:422aminoacids;47573Da SUBUNIT:Homotetramer(Probable).InteractswithSTN2,SV2A,SV2B,SV2CandRIMS1.FormsacomplexwithSV2B,syntaxin1andSNAP25(Bysimilarity). SUBCELLULARLOCATION:Cytoplasmicvesicle,secretoryvesicle,synapticvesicle.Cytoplasmicvesicle,secretoryvesicle,chromaffingranule.Note=Synapticvesiclesandchromaffingranules. DOMAIN:SwissProt:P21579ThefirstC2domainmediatesCa(2+)-dependentphospholipidbinding.&ThesecondC2domainmediatesinteractionwithSV2AandSTN2(Bysimilarity). SIMILARITY:Belongstothesynaptotagminfamily.&Contains2C2domains. |
| PhysicochemicalInformation |
|---|
| Dimensions |
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| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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