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4000-520-616
当前位置: 首页 > 产品中心 > Functional_antibody > Millipore/AB5547 | Anti-GRIP1 Antibody/AB5547/100 µg
商品详细Millipore/AB5547 | Anti-GRIP1 Antibody/AB5547/100 µg
Millipore/AB5547 | Anti-GRIP1 Antibody/AB5547/100 µg
Millipore/AB5547 | Anti-GRIP1 Antibody/AB5547/100 µg
商品编号: AB5547
品牌: 密理博
市场价: ¥5960.00
美元价: 3576.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberAB5547
BrandFamilyChemicon®
TradeName
  • Chemicon
DescriptionAnti-GRIP1Antibody
ProductInformation
FormatAffinityPurified
PresentationAffinitypurifiedimmunoglobulin.Liquidin0.02MPhosphatebufferwith0.25MNaCland0.1%sodiumazide.
StorageandShippingInformation
StorageConditionsMaintainat2-8°Cinundilutedaliquotsforupto6monthsafterdateofreceipt.
Applications
ApplicationDetectGRIP1usingthisAnti-GRIP1AntibodyvalidatedforuseinWB.
KeyApplications
  • WesternBlotting
ApplicationNotesWesternblot:2-5μg/mLonratbrainlysate.Theantibodyreactswiththe~135kDGRIP1protein.Anadditionalbandat~50-55kDmayalsobeseendependingonthesampleandconcentrationofantibodyused.

Westernblot:1-5μg/mLonhumanNT2/D1celllysate.Theantibodyreactswiththe~135kDGRIP1protein.Anadditionalbandat~37kDmayalsobeseendependingonthesampleandconcentrationofantibodyused.Immunohistochemistry:1:320onformalin-fixed,paraffinembeddedratbrainsection.Itisnecessarytopretreatthesectionwithheatinducedepitoperetrieval.Citrate,pH6.0isrecommended.Optimalworkingdilutionsmustbedeterminedbytheenduser.
BIOLOGicalInformation
ImmunogenSyntheticpeptidefromratGRIP1.
ConcentrationPleaserefertotheCertificateofAnalysisforthelot-specificconcentration.
HostRabbit
SpecificityGRIP1(glutamatereceptor-interactingprotein1).
SpeciesReactivity
  • Rat
AntibodyTypePolyclonalAntibody
EntrezGeneNumber
GeneSymbol
  • GRIP1
  • GRIPAP1
  • GRASP1
  • GRIP
  • KIAA1167
UniProtNumber
UniProtSummaryFUNCTION:SwissProt:Q9Y3R0#Mayplayaroleasalocalizedscaffoldfortheassemblyofamultiproteinsignalingcomplexandasmediatorofthetraffickingofitsbindingpartnersatspecificsubcellularlocationinneurons.
SIZE:1128aminoacids;122423Da
SUBUNIT:InteractswithEPHA7,EPHB2,KIF5A,KIF5B,KIF5C,GRIA2,GRIA3,GRIPAP1/GRASP1,PPFIA1,PPFIA4,FRAS1,PLCD4,PTPRFandliprins-alpha.CanformhomomultimersorheteromultimerswithGRIP2.FormsaternarycomplexwithGRIA2andCSPG4(Bysimilarity).InteractswithEFNB1,EFNB3andtheC-terminaltailofPRLHR.InteractswithSLC30A9(Bysimilarity).
SUBCELLULARLOCATION:Cytoplasmicvesicle.Endoplasmicreticulum.Celljunction,synapse,postsynapticcellmembrane(Bysimilarity).Note=Cytoplasmicandmembrane-associatedwithvesicles,peri-Golgicomplexesandendoplasmicreticulum.Enrichedinpost-synapticplasmamembraneandpost-synapticdensities(Bysimilarity).
DOMAIN:"SwissProt:Q9Y3R0PDZ6mediatesinteractionwiththePDZrecognitionmotifofEFNB1andEPHB2andwiththeC-terminusofPPFIA1andPPFIA4.PDZ4andPDZ5mediateinteractionwiththeC-terminusofGRIA2andGRIA3.PDZ4,PDZ5andPDZ6mediatehomomultimers.PDZ7mediatesinteractionwithPDZdomainofGRASP1.PDZ7domainbindsCSPG4.PDZ6mediatesinteractionwiththeC-terminusofliprins-alpha.PDZ1,PDZ2andPDZ3mediateinteractionwiththePDZ-bindingmotifofFRAS1(Bysimilarity).PDZ4andPDZ5mediateinteractionwithPRLHR.
SIMILARITY:Contains7PDZ(DHR)domains.
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。