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当前位置: 首页 > 产品中心 > Functional_antibody > Millipore/AB5421 | Anti-Vesicular Glutamate Transporter 3 (VGLUT3) Antibody/AB5421/50 µL
商品详细Millipore/AB5421 | Anti-Vesicular Glutamate Transporter 3 (VGLUT3) Antibody/AB5421/50 µL
Millipore/AB5421 | Anti-Vesicular Glutamate Transporter 3 (VGLUT3) Antibody/AB5421/50 µL
Millipore/AB5421 | Anti-Vesicular Glutamate Transporter 3 (VGLUT3) Antibody/AB5421/50 µL
商品编号: AB5421
品牌: 密理博
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberAB5421
ReplacesProducthasbeendiscontinuedpleaseusereplacementAB5421-I.
BrandFamilyChemicon®
TradeName
  • Chemicon
DescriptionAnti-VesicularGlutamateTransporter3(VGLUT3)Antibody
AlternateNames
  • Solutecarrierfamily17member8,deafness,autosomaldominant25
  • solutecarrierfamily17(sodium-dependentinorganicphosphatecotransporter),member8
  • vesicularglutamatetransporter3
BackgroundInformationVesicularGlutamateTransporter3(VGLUT3)isamultipassmembraneproteinrestrictedtosynapticvesiclesofglutamergicneurons.Itisspecificallyexpressedinamygdala,cerbellum,hippocampus,medulla,spinalcord,andthalamus.
ProductInformation
FormatSerum
Control
  • Brain,VGLUT3Controlpeptideavailable(CatalogueNo.AG320)
PresentationGuineapigserum.Liquid.Containsnopreservative.
StorageandShippingInformation
StorageConditionsStablefor1yearat-20ºCfromdateofreceipt.
Applications
ApplicationAnti-VesicularGlutamateTransporter3(VGLUT3)AntibodydetectslevelofVesicularGlutamateTransporter3(VGLUT3)&hasbeenpublished&validatedforuseinIC,IH&WB.
KeyApplications
  • Immunocytochemistry
  • Immunohistochemistry
  • WesternBlotting
ApplicationNotesImmunohistochemistry:
1:5,000-1:10,000dilutionofapreviouslotwasusedwithimmunofluorescenceusingcyanine-conjugatedsecondaryantibodies.

Optimalworkingdilutionsmustbedeterminedbyenduser.
BIOLOGicalInformation
ImmunogenSyntheticpeptidefromratVGLUT3protein.
ConcentrationPleaserefertotheCertificateofAnalysisforthelot-specificconcentration.
HostGuineaPig
SpecificityRecognizesVesicularGlutamateTransporter3(VGLUT3).Theantiserumhasbeentestedontissuesectionsfromtheratcentralnervoussystem(CNS)usingimmunofluorescencehistochemistry.ThestainingpatternpresentincellbodiesobtainedwiththeguineapigVGLUT3antiserumisinagreementwiththedescribedexpressionpatternofVGLUT3mRNAThestainingpatternobtainedinbothcellbodiesandnervefiberswiththeguineapigVGLUT3antiserumcoincideswiththedescribeddistributionofVGLUT3immunoreactivityobtainedwithotherVGLUT3antisera(Fremeau,2002;Gras,2002;Schäfer,2002).PreabsorptionoftheVGLUT3antiserumwiththeimmunogenpeptide(CatalognumberAG320)eliminatesallimmunostaining.
SpeciesReactivity
  • Rat
SpeciesReactivityNoteRat.Itisexpectedthattheantibodymayalsoreactwithmousebasedonsequencehomology(85%).Otherspecieshavenotyetbeentested.
AntibodyTypePolyclonalAntibody
EntrezGeneNumber
GeneSymbol
  • VGLUT3
  • VGluT3
  • SLC17A8
  • DFNA25
PurificationMethodUnpurified
UniProtNumber
UniProtSummaryFUNCTION:Mediatestheuptakeofglutamateintosynapticvesiclesatpresynapticnerveterminalsofexcitatoryneuralcells.Mayalsomediatethetransportofinorganicphosphate.
SUBCELLULARLOCATION:Cytoplasmicvesicle,secretoryvesicle,synapticvesiclemembrane(Bysimilarity).Membrane;Multi-passmembraneprotein(Potential).Celljunction,synapse,synaptosome(Bysimilarity).
TISSUESPECIFICITY:Expressedinamygdala,cerebellum,hippocampus,medulla,spinalcordandthalamus.
SIMILARITY:Belongstothemajorfacilitatorsuperfamily.Sodium/anioncotransporterfamily.VGLUTsubfamily.
SIZE:589aminoacids;64991Da
MolecularWeight~65kDa
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。