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当前位置: 首页 > 产品中心 > Functional_antibody > 微孔/AB5062P |抗囊泡GABA转运体(VGAT)抗体/AB5062P/50µ;G
商品详细微孔/AB5062P |抗囊泡GABA转运体(VGAT)抗体/AB5062P/50µ;G
微孔/AB5062P |抗囊泡GABA转运体(VGAT)抗体/AB5062P/50µ;G
微孔/AB5062P |抗囊泡GABA转运体(VGAT)抗体/AB5062P/50µ;G
商品编号: AB5062P
品牌: 密理博
市场价: ¥6980.00
美元价: 4188.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberAB5062P
BrandFamilyChemicon®
TradeName
  • Chemicon
DescriptionAnti-VesicularGABATransporter(VGAT)Antibody
AlternateNames
  • VesicularInhibitoryAminoAcidTransporter
BackgroundInformationVesicularGABATransporter(unc-47)homologueisa525aminoacidlongproteinbelongingtothefamilyofneurotransmittertransporter(1).VGATfunctionsintheuptakeofGABAandglycineintosynapticvesicles.Sincetheproteinisboundtosynapticvesicles,VGATantibodiesareexcellentMarkersofpresynapticGABAergicandglycinergicneurons.
ProductInformation
FormatAffinityPurified
Control
  • Braintissue,ratretinalysate
PresentationPurifiedrabbitpolyclonalinbuffercontainingPBSwith0.1%BSA.
StorageandShippingInformation
StorageConditionsStablefor1yearat-20ºCfromdateofreceipt.
Applications
ApplicationThisAnti-VesicularGABATransporter(VGAT)AntibodyisvalidatedforuseinELISA,IF,IH,WBforthedetectionofVesicularGABATransporter(VGAT).
KeyApplications
  • ELISA
  • Immunofluorescence
  • Immunohistochemistry
  • WesternBlotting
ApplicationNotesImmunohistochemistry/Immunofluorescence:
2-20µg/mLofapreviouslotwasusedonparaformaldehydefixedsections.

ELISA:
1:10,000–1:100,000dilutionofapreviouslotwasusedonELISA,using50-100ngofcontrolpeptide(Cat.No.AG379)perwell.

Westernblot:
1-10µg/mL(Chemiluminescencetechnique)Theexpectedmolecularweightisapproximately55-60kDa.

Optimalworkingdilutionsmustbedeterminedbytheenduser.
BIOLOGicalInformation
ImmunogenA17aminoacidpeptidesequencenearthecarboxyterminalregionofratVGAT(McIntire,S.,1997).
EpitopeC-terminus
ConcentrationPleaserefertotheCertificateofAnalysisforthelot-specificconcentration.
HostRabbit
SpecificitySpecificforVesicularGABATransporter(VGAT).VesicularGABATransporter(unc-47)homologueisa525aminoacidlongproteinbelongingtothefamilyofneurotransmittertransporter.Theimmunogenpeptideshowsnosignificanthomologywithotherknownproteins.
SpeciesReactivity
  • Rat
  • Mouse
  • Human
  • Monkey
SpeciesReactivityNoteRat.Antibodycross-reactivitywithvariousspeciesisnotknown.Theimmunogensequenceis100%conservedinmouse,humanandmonkey.
AntibodyTypePolyclonalAntibody
EntrezGeneNumber
EntrezGeneSummaryTheproteinencodedbythisgeneisanintegralmembraneproteininvolvedingamma-aminobutyricacid(GABA)andglycineuptakeintosynapticvesicles.Theencodedproteinisamemberofaminoacid/polyaminetransporterfamilyII.
GeneSymbol
  • SLC32A1
  • VIAAT
  • VGAT
  • bA122O1.1
  • hVIAAT
PurificationMethodImmunoAffinityPurified
UniProtNumber
UniProtSummaryFUNCTION:SwissProt:Q9H598#InvolvedintheuptakeofGABAandglycineintothesynapticvesicles.
SIZE:525aminoacids;57415Da
SUBCELLULARLOCATION:Cytoplasmicvesiclemembrane;Multi-passmembraneprotein(Bysimilarity).
TISSUESPECIFICITY:Retina.Expressedthroughoutthehorizontalcellsormorespecificallyattheterminals.
SIMILARITY:SwissProt:Q9H598##Belongstotheaminoacid/polyaminetransporter2family.
MolecularWeight57kDa
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。