4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:主营:分子类,蛋白类,抗体类,生化类试剂
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > Functional_antibody > 微孔/AB3830 |抗小窝蛋白-1抗体,磷酸特异性(Tyr14)/AB3830/100µ;L
商品详细微孔/AB3830 |抗小窝蛋白-1抗体,磷酸特异性(Tyr14)/AB3830/100µ;L
微孔/AB3830 |抗小窝蛋白-1抗体,磷酸特异性(Tyr14)/AB3830/100µ;L
微孔/AB3830 |抗小窝蛋白-1抗体,磷酸特异性(Tyr14)/AB3830/100µ;L
商品编号: AB3830
品牌: 密理博
市场价: ¥7600.00
美元价: 4560.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberAB3830
BrandFamilyChemicon®
TradeName
  • Chemicon
DescriptionAnti-Caveolin-1Antibody,phospho-specific(Tyr14)
ProductInformation
FormatAffinityPurified
PresentationProteinAandpeptideaffinitypurifiedimmunoglobulin.Liquidin10mMsodiumHEPES,pH7.5,150mMNaCl,100μg/mlBSA,with50%glycerol.
StorageandShippingInformation
StorageConditionsMaintainat-20ºCfor12months,donotaliquot.
Applications
ApplicationThisAnti-Caveolin-1Antibody,phospho-specific(Tyr14)isvalidatedforuseinIP,WBforthedetectionofCaveolin-1.
KeyApplications
  • Immunoprecipitation
  • WesternBlotting
ApplicationNotesWesternblotting1:1,000(forbestresults,incubatemembranewithdilutedantibodyin5%BSA,1XTBS,0.1%Tween-20at4°Cwithgentleshaking,overnight)

Immunoprecipitation1:50

Optimalworkingdilutionsmustbedeterminedbytheenduser.
BIOLOGicalInformation
ImmunogenKLH-conjugated,syntheticphospho-peptidecorrespondingtoresiduessurroundingTyr14ofhumancaveolin-1
Epitopephospho-specific(Tyr14)
HostRabbit
SpecificityRecognizescaveolin-1onlywhenphosphorylatedattyrosine14.Thisantibodydoesnotcross-reactwithcaveolin-2,-3orcaveolin-1beta,ortheshortisoformofcaveolin-1.
SpeciesReactivity
  • Human
  • Mouse
  • Monkey
  • Rat
AntibodyTypePolyclonalAntibody
EntrezGeneNumber
EntrezGeneSummaryThescaffoldingproteinencodedbythisgeneisthemaincomponentofthecaveolaeplasmamembranesfoundinmostcelltypes.TheproteinlinksintegrinsubunitstothetyrosinekinaseFYN,aninitiatingstepincouplingintegrinstotheRas-ERKpathwayandpromotingcellcycleprogression.ThegeneisatumorsuppressorgenecandidateandanegativeregulatoroftheRas-p42/44MAPkinasecascade.CAV1andCAV2arelocatednexttoeachotheronchromosome7andexpresscolocalizingproteinsthatformastablehetero-oligomericcomplex.ByusingalternativeinitiationcodonsinthesamereADIngframe,twoisoforms(alphaandbeta)areencodedbyasingletranscriptfromthisgene.
GeneSymbol
  • CAV1
  • MSTP085
  • CAV
  • VIP21
  • Caveolin-1.
Modifications
  • Phosphorylation
UniProtNumber
UniProtSummaryFUNCTION:SwissProt:Q03135#Mayactasascaffoldingproteinwithincaveolarmembranes.InteractsdirectlywithG-proteinalphasubunitsandcanfunctionallyregulatetheiractivity(Bysimilarity).
SIZE:178aminoacids;20472Da
SUBUNIT:Homooligomer.InteractswithGLIPR2,NOSTRIN,SNAP25andsyntaxin.
SUBCELLULARLOCATION:Golgiapparatusmembrane;Peripheralmembraneprotein;Cytoplasmicside.Cellmembrane,caveola;Peripheralmembraneprotein;Cytoplasmicside.Note=Membraneproteinofcaveolae.Potentialhairpin-likestructureinthemembrane.
TISSUESPECIFICITY:Inmuscleandlung,lesssoinliver,brainandkidney.
PTM:TheinitiatormethionineforisoformBetaisremovedduringorjustaftertranslation.ThenewN-terminalaminoacidisthenN-acetylated.
SIMILARITY:SwissProt:Q03135##Belongstothecaveolinfamily.
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。