微孔/AB3830 |抗小窝蛋白-1抗体,磷酸特异性(Tyr14)/AB3830/100µ;L
市场价:
¥7600.00
美元价:
4560.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | |
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CatalogueNumber | AB3830 |
BrandFamily | Chemicon® |
TradeName |
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Description | Anti-Caveolin-1Antibody,phospho-specific(Tyr14) |
ProductInformation | |
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Format | AffinityPurified |
Presentation | ProteinAandpeptideaffinitypurifiedimmunoglobulin.Liquidin10mMsodiumHEPES,pH7.5,150mMNaCl,100μg/mlBSA,with50%glycerol. |
StorageandShippingInformation | |
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StorageConditions | Maintainat-20ºCfor12months,donotaliquot. |
BIOLOGicalInformation | |
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Immunogen | KLH-conjugated,syntheticphospho-peptidecorrespondingtoresiduessurroundingTyr14ofhumancaveolin-1 |
Epitope | phospho-specific(Tyr14) |
Host | Rabbit |
Specificity | Recognizescaveolin-1onlywhenphosphorylatedattyrosine14.Thisantibodydoesnotcross-reactwithcaveolin-2,-3orcaveolin-1beta,ortheshortisoformofcaveolin-1. |
SpeciesReactivity |
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AntibodyType | PolyclonalAntibody |
EntrezGeneNumber | |
EntrezGeneSummary | Thescaffoldingproteinencodedbythisgeneisthemaincomponentofthecaveolaeplasmamembranesfoundinmostcelltypes.TheproteinlinksintegrinsubunitstothetyrosinekinaseFYN,aninitiatingstepincouplingintegrinstotheRas-ERKpathwayandpromotingcellcycleprogression.ThegeneisatumorsuppressorgenecandidateandanegativeregulatoroftheRas-p42/44MAPkinasecascade.CAV1andCAV2arelocatednexttoeachotheronchromosome7andexpresscolocalizingproteinsthatformastablehetero-oligomericcomplex.ByusingalternativeinitiationcodonsinthesamereADIngframe,twoisoforms(alphaandbeta)areencodedbyasingletranscriptfromthisgene. |
GeneSymbol |
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Modifications |
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UniProtNumber | |
UniProtSummary | FUNCTION:SwissProt:Q03135#Mayactasascaffoldingproteinwithincaveolarmembranes.InteractsdirectlywithG-proteinalphasubunitsandcanfunctionallyregulatetheiractivity(Bysimilarity). SIZE:178aminoacids;20472Da SUBUNIT:Homooligomer.InteractswithGLIPR2,NOSTRIN,SNAP25andsyntaxin. SUBCELLULARLOCATION:Golgiapparatusmembrane;Peripheralmembraneprotein;Cytoplasmicside.Cellmembrane,caveola;Peripheralmembraneprotein;Cytoplasmicside.Note=Membraneproteinofcaveolae.Potentialhairpin-likestructureinthemembrane. TISSUESPECIFICITY:Inmuscleandlung,lesssoinliver,brainandkidney. PTM:TheinitiatormethionineforisoformBetaisremovedduringorjustaftertranslation.ThenewN-terminalaminoacidisthenN-acetylated. SIMILARITY:SwissProt:Q03135##Belongstothecaveolinfamily. |
PhysicochemicalInformation |
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Dimensions |
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MaterialsInformation |
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MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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