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当前位置: 首页 > 产品中心 > Functional_antibody > Millipore/AB1576 | Anti-Cysteine String Protein Antibody/AB1576/50 µL
商品详细Millipore/AB1576 | Anti-Cysteine String Protein Antibody/AB1576/50 µL
Millipore/AB1576 | Anti-Cysteine String Protein Antibody/AB1576/50 µL
Millipore/AB1576 | Anti-Cysteine String Protein Antibody/AB1576/50 µL
商品编号: AB1576
品牌: 密理博
市场价: ¥5960.00
美元价: 3576.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberAB1576
BrandFamilyChemicon®
TradeName
  • Chemicon
DescriptionAnti-CysteineStringProteinAntibody
AlternateNames
  • CSP
  • DnaJHomologueSubfamilyCmember5
BackgroundInformationCysteine-stringproteinsaremembrane-boundproteinsassociatedprimarilywithnerveendingsandsynapticvesiclesinthebrainwheretheyserveanimportantroleinpresynapticfunctionandmaybeinvolvedincalcium-dependentneurotransmitterreleaseatnerveendings.CSPspossesastrechofaminoacidshighlyenrichedincysteineresiduesthatarepost-translationallypalmitoylated.CSPsmayfunctionashomodimers.
ProductInformation
FormatSerum
Control
  • POSITIVECONTROL:brainsamples
PresentationLiquidrabbitserumcontainingnopreservatives
StorageandShippingInformation
StorageConditionsStoreat-20°Cinundilutedaliquotsforupto12monthsfromdateofreceipt.Avoidrepeatedfreeze/thawcycles.
Applications
ApplicationThisAnti-CysteineStringProteinAntibodyisvalidatedforuseinWB,IC,IHforthedetectionofCysteineStringProtein.
KeyApplications
  • WesternBlotting
ApplicationNotesImmunohistochemistryonformalinfixedtissue:1:1,000.(RecommendCat.No.AB1576P).ImmunocytochemistryonPC-12cells:1:1,000.(RecommendCat.No.AB1576P).Immunoblotting:1:5,000.CSPsshouldberesolvedon12-15%SDS-PAGEgelsunderNON-REDUCINGconditions.CSPstypicallymigrateas33-35kDaspeciesinvertebratesamples(dimersmayalsobeseen).IfonemustperformSDS-PAGEunderreducingconditions,itisnecessarytoalkylatetheCSPstopreventsmearing.ToensureproperidentificationofCSPs,samplesmaybedeacylatedbytreatmentwith1Mneutralhydroxylamineor0.1MKOHinmethanolresultingina6-7kDashiftinelectrophoreticmobilityoftheCSPband.Deacylationwillusuallyresultimnsomelossofreactivityonwesternblotssosufficientproteinshouldbeloaded.Alternatively,becauseallCSPsappeartobeacidic(approximatepIof4.6-4.8)2-DgelelectrophoresismaybeusefulltodistinguishsomeCSPs.Finally,somesampletreatmentsmaycausepartialdeacylationofCSPsresultinginasmearofimmunoreactivitybelowthemassofthefattyacylatedmonomer.Optimalworkingdilutionsmustbedeterminedbytheenduser.
BIOLOGicalInformation
ImmunogenRecombinantratcysteine-stringproteinwiththecysteinestringdeleted.
HostRabbit
SpecificityCysteine-stringProtein.TheantibodyrecognizesprimarilythealphaisoformofCSPwithsomerecognitionofthebetaisoforms.Slightreactivitywiththegammaisoformsmaybedetected.
SpeciesReactivity
  • All
AntibodyTypePolyclonalAntibody
EntrezGeneNumber
GeneSymbol
  • DNAJC5
  • CSP
  • DKFZP434N1429
  • FLJ13070
  • DKFZp761N1221
  • FLJ00118
UniProtNumber
UniProtSummaryFUNCTION:SwissProt:Q9H3Z4#Mayhaveanimportantroleinpresynapticfunction.Maybeinvolvedincalcium-dependentneurotransmitterreleaseatnerveendings(Bysimilarity).
SIZE:198aminoacids;22149Da
SUBCELLULARLOCATION:Membrane;Lipid-anchor(Bysimilarity).Melanosome.Note=IdentifiedbymassspectrometryinmelanosomefractionsfromstageItostageIV.
TISSUESPECIFICITY:Expressedinpancreas,kidney,skeletalmuscle,liver,lung,placenta,brainandheart.
PTM:Fattyacylated.Heavilypalmitoylatedinthecysteinestringmotif(Bysimilarity).
SIMILARITY:SwissProt:Q9H3Z4##Contains1Jdomain.
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。