密理博/AB15102 |抗薄荷-1抗体/AB15102/100µ;L
市场价:
¥0.00
美元价:
0.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | AB15102 |
| BrandFamily | Chemicon® |
| TradeName |
|
| Description | Anti-Mint-1Antibody |
| ProductInformation | |
|---|---|
| Format | Serum |
| Presentation | Liquid |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainat-20degCinundilutedaliquotsforupto12monthsafterdateofreceipt.Avoidrepeatedfreeze/thawcycles. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | Syntheticpeptidefromrat. |
| Host | Rabbit |
| Specificity | Mint-1.ByWesternblottheantibodyrecognizesabandat~130kDainratbrainlysate. |
| SpeciesReactivity |
|
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | TheproteinencodedbythisgeneisamemberoftheX11proteinfamily.ItisaneuronaladaptorproteinthatinteractswiththeAlzheimer"sdiseaseamyloidprecursorprotein(APP).ItstABIlisesAPPandinhibitsproductionofproteolyticAPPfragmentsincludingtheAbetapeptidethatisdepositedinthebrainsofAlzheimer"sdiseasepatients.Thisgeneproductisbelievedtobeinvolvedinsignaltransductionprocesses.Itisalsoregardedasaputativevesiculartraffickingproteininthebrainthatcanformacomplexwiththepotentialtocouplesynapticvesicleexocytosistoneuronalcelladhesion. |
| GeneSymbol |
|
| PurificationMethod | Serum |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:Q02410#PutativefunctioninsynapticvesicleexocytosisbybindingtoMunc18-1,anessentialcomponentofthesynapticvesicleexocytoticmachinery.Maymodulateprocessingofthebeta-amyloidprecursorprotein(APP)andhenceformationofbeta-APP. SIZE:837aminoacids;92865Da SUBUNIT:PartofamultimericcomplexcontainingMunc18-1andsyntaxin-1.Alsopartofthebrain-specificheterotrimericcomplexLIN-10/X11-alpha,LIN-2/CASK,andLIN7.Bindstothecytoplasmicdomainofamyloidprotein(APP). TISSUESPECIFICITY:Brainandspinalcord. DOMAIN:SwissProt:Q02410ComposedofanN-terminaldomainthatbindsMunc18-1andLIN-2/CASK,amiddlephosphotyrosine-bindingdomain(PID/PTB)thatmediatesbindingwiththecytoplasmicdomainofthebeta-amyloidprecursorprotein,andtwoC-terminalPDZdomainsthoughttoattachproteinstotheplasmamembrane. SIMILARITY:Contains2PDZ(DHR)domains.&Contains1PIDdomain. |
| PhysicochemicalInformation |
|---|
| Dimensions |
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| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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