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Millipore/09-142 | Anti-phospho-ACK1 (Tyr284) Antibody/09-142/100 µL
Millipore/09-142 | Anti-phospho-ACK1 (Tyr284) Antibody/09-142/100 µL
市场价：
¥8420.00
美元价：
5052.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | 09-142 |
| BrandFamily | Upstate |
| TradeName |
|
| Description | Anti-phospho-ACK1(Tyr284)Antibody |
| AlternateNames |
|
| ProductInformation | |
|---|---|
| Format | AffinityPurified |
| Control |
|
| Presentation | ImmunoaffinityPurifiedrabbitpolyclonalIgGin0.02MPBS,0.25Msodiumchloride(pH7.6)containing0.1%sodiumazideand30%glycerol. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainfor2yearsat-20°Cfromdateofshipment.Aliquottoavoidrepeatedfreezingandthawing.Formaximumrecoveryofproduct,centrifugetheoriginalvialafterthawingandpriortoremovingthecap. |
| Applications | |
|---|---|
| Application | Detectphospho-ACK1(Tyr284)usingthisAnti-phospho-ACK1(Tyr284)AntibodyvalidatedforuseinWB. |
| KeyApplications |
|
| BIOLOGicalInformation | |
|---|---|
| Immunogen | KLHconjugatedsyntheticpeptidecorrespondingtoaminoacidssurroundingTyr284ofhumanACK1. |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Rabbit |
| Specificity | RecognizesACK1phosphorylatedonTyrosineresidue284. |
| Isotype | IgG |
| SpeciesReactivity |
|
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | ThisgeneencodesatyrosinekinasethatbindsCdc42HsinitsGTP-boundformandinhibitsboththeintrinsicandGTPase-activatingprotein(GAP)-stimulatedGTPaseactivityofCdc42Hs.Thisbindingismediatedbyauniquesequenceof47aminoacidsC-terminaltoanSH3domain.TheproteinmaybeinvolvedinaregulatorymechanismthatsustainstheGTP-boundactiveformofCdc42Hsandwhichisdirectlylinkedtoatyrosinephosphorylationsignaltransductionpathway.Severalalternativelysplicedtranscriptvariantshavebeenidentifiedfromthisgene,butthefull-lengthnatureofonlytwotranscriptvariantshasbeendetermined. |
| GeneSymbol |
|
| Modifications |
|
| PurificationMethod | ImmunoAffinityPurified |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:Q07912#DownstreameffectorofCDC42whichmediatesCDC42-dependentcellmigrationviaphosphorylationofBCAR1.Bindstobothpoly-andmono-ubiquitinandregulatesligand-induceddegradationofEGFR.Participatesinclathrin-mediatedendocytosis.Maybeinvolvedbothinadultsynapticfunctionandplasticityandinbraindevelopment. COFACTOR:Magnesium. SIZE:1036aminoacids;114327Da SUBUNIT:InteractswithCDC42.InteractswithactivatedCSPG4. SUBCELLULARLOCATION:Cellmembrane(Bysimilarity). SIMILARITY:SwissProt:Q07912##Belongstotheproteinkinasesuperfamily.Tyrproteinkinasefamily.&Contains1CRIBdomain.&Contains1proteinkinasedomain.&Contains1SH3domain. |
| MolecularWeight | 114kDa |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
|---|
品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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