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Millipore/07-577 | Anti-Stargazin/Cacng2 Antibody, CT/07-577/100 µg
Millipore/07-577 | Anti-Stargazin/Cacng2 Antibody, CT/07-577/100 µg
市场价：
¥7400.00
美元价：
4440.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | 07-577 |
| BrandFamily | Upstate |
| TradeName |
|
| Description | Anti-Stargazin/Cacng2Antibody,CT |
| AlternateNames |
|
| BackgroundInformation | Stargazinbelongstoagroupcalledvoltagegatedcalciumchannels(VGCCs)whicharepresentinmostexcitablecells.StargazinisthoughttostABIlizethecalciumchannelinaninactivated(closed)state. Therearefivehighvoltageactivatedcalciumchanneltypes(L,N,P,Q,andR)andonelowvoltageactivatedchanneltype(T).Eachofthesechannelsexistsasaheteromultimerofa1,b,a2/dandgsubunitswiththevoltageactivatedcalciumchannelfunctioncarriedbytheasubunits.VGCCsexertspatialandtemporalcontrolovercellularcalciumconcentrationsandservetomodulateneurotransmitterrelease,hormonesecretion,musclecontraction,electricalactivity,cellmetabolismandproliferation,geneexpression,andneuronalsurvival. |
| ProductInformation | |
|---|---|
| Format | Purified |
| Control |
|
| Presentation | PurifiedrabbitpolyclonalIgGinbuffercontaining0.1MTris-glycine,pH7.4,0.15MNaCl,0.05%sodiumazidebeforetheadditionofglycerolto30%. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Stablefor1yearat-20ºCfromdateofreceipt. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | KLH-conjugated,syntheticpeptidecorrespondingtoaminoacids305-323(KDSKDSLHANTANRRTTPV)ofratStargazin. |
| Epitope | C-terminus |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Rabbit |
| Specificity | RecognizesStargazin,MW~36-39kDa. |
| Isotype | IgG |
| SpeciesReactivity |
|
| SpeciesReactivityNote | Rat.Predictedtocross-reactwithmousebasedonsequencesimilarity. |
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | L-typecalciumchannelsarecomposedoffivesubunits.Theproteinencodedbythisgenerepresentsoneofthesesubunits,gamma,andisoneofseveralgammasubunitproteins.Itisanintegralmembraneproteinthatisthoughttostabilizethecalciumchannelinaninactive(closed)state.Thisproteinissimilartothemousestargazinprotein,mutationsinwhichhavebeenassociatedwithabsenceseizures,alsoknownaspetit-malorspike-waveseizures.ThisgeneisamemberoftheneuronalcalciumchannelgammasubunitgenesubfamilyofthePMP-22/EMP/MP20family. |
| GeneSymbol |
|
| PurificationMethod | ProteinAPurfied |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:Q9Y698#Thoughttostabilizethecalciumchannelinaninactivated(closed)state. SIZE:323aminoacids;35966Da SUBUNIT:TheL-typecalciumchanneliscomposedoffivesubunits:alpha-1,alpha-2/delta,betaandgamma.InteractswiththePDZdomainsofDLG4/PSD-95andDLG1/SAP97.MayinteractwithGOPC(Bysimilarity). SUBCELLULARLOCATION:Membrane;Multi-passmembraneprotein. TISSUESPECIFICITY:Brain. PTM:PhosphorylationofThr-321impairsinteractionwithDLG1andDLG4. SIMILARITY:SwissProt:Q9Y698##BelongstothePMP-22/EMP/MP20family.CACNGsubfamily. |
| MolecularWeight | ~36-39kDa |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
|---|
品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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