当前位置：
首页
>
产品中心 >
Functional_antibody >
Millipore/04-592 | Anti-Flotillin-1 Antibody, rabbit monoclonal, clone EP446Y/04-592/100 µL
Millipore/04-592 | Anti-Flotillin-1 Antibody, rabbit monoclonal, clone EP446Y/04-592/100 µL
市场价：
¥0.00
美元价：
0.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | 04-592 |
| BrandFamily | Upstate |
| TradeName |
|
| Description | Anti-Flotillin-1Antibody,rabbitmonoclonal,cloneEP446Y |
| AlternateNames |
|
| BackgroundInformation | Flotillin-1,alsoknownasReggie-2,belongstoalargerfamilyofproteinsthatshareanevolutionarilyconservedstomatin/prohibitin/flotillin/HflK/C(SPFH)domain(1).Flotillin-1isalipidraft-associatedproteinthathasbeenimplicatedinvariouscellularprocesses.Flotillinwasfirstfoundincellsthatlackmorphologicallydefinablecaveolae,aswellasinnon-caveolarmembranes(2)andwassubsequentlyidentifiedinlowdensitydetergent-insolublecomplexesofendothelialcells,wheretheyweretermedflotillins(3).Aswellasitspostulatedroleinneuronalregeneration,flotilllin-1hasbeenimplicatedininsulinsignalingtotriggerglucosetransporterredistributioninADIpocytes(4)Flotillinalsoassociateswithphagosomesinmacrophages(5). |
| ProductInformation | |
|---|---|
| Format | Purified |
| Presentation | Buffer:50mMTris-Glycine(pH7.4),0.15MNaCl,40%Glycerol,0.01%sodiumazideand0.05%BSA. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Storeat-20°C.Stablefor12monthsfromdateofreceipt. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | AsyntheticpeptidecorrespondingtoresiduesinhumanFlotillin-1. |
| Clone | EP446Y |
| Host | Rabbit |
| Specificity | RecognizesHuman,MouseFlotillin-1. |
| SpeciesReactivity |
|
| SpeciesReactivityNote | Human,Mouse(positivecontrol:K562celllysate) |
| AntibodyType | MonoclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | Caveolaearesmalldomainsontheinnercellmembraneinvolvedinvesiculartraffickingandsignaltransduction.FLOT1encodesacaveolae-associated,integralmembraneprotein.Thefunctionofflotillin1hasnotbeendetermined. |
| GeneSymbol |
|
| PurificationMethod | ProteinAPurfied |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:O75955#Mayactasascaffoldingproteinwithincaveolarmembranes,functionallyparticipatinginformationofcaveolaeorcaveolae-likevesicles. SIZE:427aminoacids;47355Da SUBUNIT:Hetero-oligomericcomplexofflotillin-1andflotillin-2andcaveolin-1andcaveolin-2(Bysimilarity). SUBCELLULARLOCATION:Cellmembrane,caveola;Peripheralmembraneprotein.Melanosome.Note=Membrane-associatedproteinofcaveolae.IdentifiedbymassspectrometryinmelanosomefractionsfromstageItostageIV. SIMILARITY:SwissProt:O75955##Belongstotheband7/mec-2family.Flotillinsubfamily. |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
|---|
品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
联络我们
