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Millipore/AB9094 | Anti-Sodium Pump (Na+ pump (Na+-K+-ATPase)) α 2 Isoform Antibody/AB9094/100 µL
Millipore/AB9094 | Anti-Sodium Pump (Na+ pump (Na+-K+-ATPase)) α 2 Isoform Antibody/AB9094/100 µL
市场价：
¥0.00
美元价：
0.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | AB9094 |
| BrandFamily | Chemicon® |
| TradeName |
|
| Description | Anti-SodiumPump(Na+pump(Na+-K+-ATPase))α2IsoformAntibody |
| ProductInformation | |
|---|---|
| Format | Serum |
| Control |
|
| Presentation | Rabbitserum.Liquid. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainat-20°Cinundilutedforupto6monthsafterdateofreceipt.Avoidrepeatedfreeze/thawcycles. |
| Applications | |
|---|---|
| Application | DetectSodiumPump(Na+pump(Na+-K+-ATPase))α2IsoformusingthisAnti-SodiumPump(Na+pump(Na+-K+-ATPase))α2IsoformAntibodyvalidatedforuseinIP&WB. |
| KeyApplications |
|
| ApplicationNotes | Westernblot:1:2,000-1:4,000forbrainand1:1,000-1:2,000formuscle.Theantibodyrecognizesaspecificbandat~100kDa.Heatthesampleto37°CinstandardLaemmlifor30minutes(don"tboil).Boilingcausessomesodiumpumpheteromerstoclenchtogethergivingabandat~150kDa.SuggesteddilutionbufferisTBSTwith1%BSAcontainingapreservative.Suggestedgelpercentageis7.5%. Immunoprecipiation:seeJournalofBIOLOGicalChemistry(2004)279:2885-2893. Optimalworkingdilutionsmustbedeterminedbytheenduser. |
| BiologicalInformation | |
|---|---|
| Immunogen | Syntheticpeptide. |
| Host | Rabbit |
| Specificity | ReactswithSodiumPump(Na+pump(Na+-K+-ATPase))alpha2isoform.TheantibodydoesnotcrossreactwithotherNa+-K+-ATPasealphaisoforms. |
| SpeciesReactivity |
|
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | TheproteinencodedbythisgenebelongstothefamilyofP-typecationtransportATPases,andtothesubfamilyofNa+/K+-ATPases.Na+/K+-ATPaseisanintegralmembraneproteinresponsIBLeforestablishingandmaintainingtheelectRochemicalgrADIentsofNaandKionsacrosstheplasmamembrane.Thesegradientsareessentialforosmoregulation,forsodium-coupledtransportofavarietyoforganicandinorganicmolecules,andforelectricalexcitABIlityofnerveandmuscle.Thisenzymeiscomposedoftwosubunits,alargecatalyticsubunit(alpha)andasmallerglycoproteinsubunit(beta).ThecatalyticsubunitofNa+/K+-ATPaseisencodedbymultiplegenes.Thisgeneencodesanalpha2subunit. |
| GeneSymbol |
|
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P50993#Thisisthecatalyticcomponentoftheactiveenzyme,whichcatalyzesthehydrolysisofATPcoupledwiththeexchangeofsodiumandpotassiumionsacrosstheplasmamembrane.Thisactioncreatestheelectrochemicalgradientofsodiumandpotassium,providingtheenergyforactivetransportofvariousnutrients. SIZE:1020aminoacids;112265Da SUBUNIT:Composedofthreesubunits:alpha(catalytic),betaandgamma. SUBCELLULARLOCATION:Membrane;Multi-passmembraneprotein. DISEASE:SwissProt:P50993#DefectsinATP1A2arethecauseoffamilialhemiplegicmigraine2(FHM2)[MIM:602481].Familialhemiplegicmigraineisarare,severe,autosomaldominantsubtypeofmigrainecharacterizedbyauraandsomehemiparesis.&DefectsinATP1A2areacauseofalternatinghemiplegiaofchildhood(AHC)[MIM:104290].AHCistypicallydistinguishedfromfamilialhemiplegicmigrainebyinfantileonsetofthesymptomsandhighprevalenceofassociatedneurologicaldeficitsthatbecomeincreasinglyobviouswithage. SIMILARITY:SwissProt:P50993##BelongstothecationtransportATPase(P-type)family.TypeIICsubfamily. |
| PhysicochemicalInformation |
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| Dimensions |
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| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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