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Millipore/AB5925 | Anti-Protein Gene Product 9.5 Antibody/AB5925/50 µL

Millipore/AB5925 | Anti-Protein Gene Product 9.5 Antibody/AB5925/50 µL
市场价:
¥6780.00
美元价:
4068.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | |
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CatalogueNumber | AB5925 |
BrandFamily | Chemicon® |
TradeName |
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Description | Anti-ProteinGeneProduct9.5Antibody |
AlternateNames |
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ProductInformation | |
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Format | Serum |
Presentation | Liquidwith0.05%sodiumazide. |
StorageandShippingInformation | |
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StorageConditions | Maintainat-20°Cinundilutedforupto6months.Avoidrepeatedfreeze/thawcycles. |
BIOLOGicalInformation | |
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Immunogen | Syntheticpeptidecorrespondingtoaminoacids108-127ofsolublecytoplasmichumanPGP9.5. |
Host | Rabbit |
Specificity | ProteinGeneProduct9.5(PGP9.5). |
SpeciesReactivity |
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AntibodyType | PolyclonalAntibody |
EntrezGeneNumber | |
EntrezGeneSummary | UCHL1isamemberofagenefamilywhoseproductshydrolyzesmallC-terminaladductsofubiquitintogeneratetheubiquitinmonomer.ExpressionofUCHL1ishighlyspecifictoneuronsandtocellsofthediffuseneuroendocrinesystemandtheirtumors.Itispresentinallneurons(Doranetal.,1983[PubMed6343558]).[suppliedbyOMIM] |
GeneSymbol |
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UniProtNumber | |
UniProtSummary | FUNCTION:SwissProt:P09936#Ubiquitin-proteinhydrolaseinvolvedbothintheprocessingofubiquitinprecursorsandofubiquitinatedproteins.ThisenzymeisathiolproteasethatrecognizesandhydrolyzesapeptidebondattheC-terminalglycineofubiquitin.Alsobindstofreemonoubiquitinandmaypreventitsdegradationinlysosomes.ThehomodimermayhaveATP-independentubiquitinligaseactivity. SIZE:223aminoacids;24824Da SUBUNIT:Homodimer.InteractswithSNCA(Bysimilarity).InteractswithCOPS5. SUBCELLULARLOCATION:Cytoplasm. TISSUESPECIFICITY:Foundinneuronalcellbodiesandprocessesthroughouttheneocortex(atproteinlevel).Expressedinneuronsandcellsofthediffuseneuroendocrinesystemandtheirtumors.Weaklyexpressedinovary. PTM:O-glycosylated(Bysimilarity). DISEASE:SwissProt:P09936#OxidationofMet-1,Met-6,Met-12,Met-124andMet-179tomethioninesulfoxide,andoxidationofCys-220tocysteinesulfonicacidhavebeenobservedinbrainsfromAlzheimerdisease(AD)andParkinsondisease(PD)patients.InAD,UCHL1wasfoundtobeassociatedwithneurofibrillarytangles. SIMILARITY:SwissProt:P09936##BelongstothepeptidaseC12family. MISCELLANEOUS:IncontrasttoUCHL3,doesnothydrolyzeapeptidebondattheC-terminalglycineofNEDD8. |
PhysicochemicalInformation |
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Dimensions |
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MaterialsInformation |
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MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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