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当前位置: 首页 > 产品中心 > Functional_antibody > Millipore/ABN184 |抗神经肽-1抗体,EC结构域/ABN184/100µ;G
商品详细Millipore/ABN184 |抗神经肽-1抗体,EC结构域/ABN184/100µ;G
Millipore/ABN184 |抗神经肽-1抗体,EC结构域/ABN184/100µ;G
Millipore/ABN184 |抗神经肽-1抗体,EC结构域/ABN184/100µ;G
商品编号: ABN184
品牌: 密理博
市场价: ¥6360.00
美元价: 3816.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberABN184
DescriptionAnti-Neuropilin-1Antibody,ECdomain
AlternateNames
  • CD304
  • BDCA4
  • Neuropilin-1
  • Vascularendothelialcellgrowthfactor165receptor
BackgroundInformationNeuropilin-1(NRP1),alsoknownasVascularendothelialcellgrowthfactor165receptor(VEGF165R),isatype1membraneproteinwiththreedistinctfunctions.First,itcanmediatecelladhesionviaaheterophilicmolecularinteraction.Second,inneuronalcells,neuropilin-1bindstheclass3semaphorins,whichareneuronalchemorepellents,andplaysaroleinthedirectionalguidanceofaxons.ItisexpectedtoformcomplexeswiththeplexinAsubfamilymembersandmediatethesemaphorin-elicitedinhibitorysignalsintoneurons.Third,inendothelialcells,neuropilin-1bindsapotentendothelialcellmitogen,vascularendothelialgrowthfactor(VEGF)165,andregulatesvesselformation.
ProductInformation
FormatAffinityPurified
Control
  • Humanplacentatissuelysate
PresentationPurifiedrabbitpolyclonalinbuffercontaining0.1MTris-Glycine(pH7.4),150mMNaClwith0.05%sodiumazide.
StorageandShippingInformation
StorageConditionsStablefor1yearat2-8°Cfromdateofreceipt.
Applications
ApplicationAnti-Neuropilin-1Antibody,ECdomainisahighlyspecificrabbitpolyclonalantibody,thattargetsNeuropilin&hasbeentestedinwesternblotting,IHC&FlowCytometry.
KeyApplications
  • WesternBlotting
  • Immunohistochemistry
  • FlowCytometry
ApplicationNotesImmunohistochemistryAnalysis:A1:4,000dilutionfromarepresentativelotdetectedNeuropilin-1inhumankidneytissue.
FlowCytometryAnalysis:4µgofthisantibodydetectedNeuropilin-1inHT1080cells.
BIOLOGicalInformation
ImmunogenKLH-conjugatedlinearpeptidecorrespondingtotheextracellulardomainofhumanNeuropilin-1.
EpitopeExtracellulardomain
ConcentrationPleaserefertotheCertificateofAnalysisforthelot-specificconcentration.
HostRabbit
SpecificityThisantibodyrecognizestheextracellulardomainofNeuropilin-1.
SpeciesReactivity
  • Human
SpeciesReactivityNoteDemonstratedtoreactwithHuman.PredictedtoreactwithCanine,Horse,Primate,Mouse,Rat,andBovinebasedon100%sequencehomology.
AntibodyTypePolyclonalAntibody
EntrezGeneNumber
GeneSymbol
  • NRP1
  • NRP
  • VEGF165R
PurificationMethodAffinityPurfied
UniProtNumber
MolecularWeight~90kDaobserved.Anuncharacterizedbandmayappearinsomelysates.Thecalculatedmolecularweightis103kDa,howeverNeuropilin-1hasbeenshownasa~90kDa,~120kDa,and~130kDabandinsomewesternblots(Gagnon,M.L.,etal.(2000).PNAS.97(6):2573-2578).
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。