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当前位置: 首页 > 产品中心 > Functional_antibody > Millipore/AB9604 | Anti-Semaphorin 3A Antibody, central region/AB9604/100 µL
商品详细Millipore/AB9604 | Anti-Semaphorin 3A Antibody, central region/AB9604/100 µL
Millipore/AB9604 | Anti-Semaphorin 3A Antibody, central region/AB9604/100 µL
Millipore/AB9604 | Anti-Semaphorin 3A Antibody, central region/AB9604/100 µL
商品编号: AB9604
品牌: 密理博
市场价: ¥5960.00
美元价: 3576.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberAB9604
BrandFamilyChemicon®
TradeName
  • Chemicon
DescriptionAnti-Semaphorin3AAntibody,centralregion
ProductInformation
FormatAffinityPurified
PresentationLiquidinPBScontaining50%glycerol,1mg/mLBSAand0.05%sodiumazide.
StorageandShippingInformation
StorageConditionsMaintainat-20°Cinundilutedaliquotsforupto6monthsafterdateofreceipt.Avoidrepeatedfreeze/thawcycles.
Applications
ApplicationAnti-Semaphorin3AAntibody,centralregiondetectslevelofSemaphorin3A&hasbeenpublished&validatedforuseinWB.
KeyApplications
  • WesternBlotting
ApplicationNotesWesternblot:1:1,000onneonatalratbrainandrecombinanthumanSemaphorin3A/Fcchimera(95/125kDa).Theantibodyreactswiththe~95kDaprotein.ThesuggestedantibodydiluentisPBScontaining5%non-fatmilkand0.04%Tween20.

Optimalworkingdilutionsmustbedeterminedbytheenduser.
BIOLOGicalInformation
ImmunogenSyntheticpeptidefromthecentralregionofhumansemaphorin3A.
HostRabbit
SpecificitySemaphorin3A.Theimmunogensequencehaslowhomologywithothersemaphorinfamilymembers.
SpeciesReactivity
  • Human
  • Rat
SpeciesReactivityNoteItisexpectedthattheantibodywillalsoreactwithmouse.
AntibodyTypePolyclonalAntibody
EntrezGeneNumber
EntrezGeneSummaryThisgeneisamemberofthesemaphorinfamilyandencodesaproteinwithanIg-likeC2-type(immunoglobulin-like)domain,aPSIdomainandaSemadomain.Thissecretedproteincanfunctionaseitherachemorepulsiveagent,inhibitingaxonaloutgrowth,orasachemoattractiveagent,stimulatingthegrowthofapicaldendrites.Inbothcases,theproteinisvitalfornormalneuronalpatterndevelopment.Increasedexpressionofthisproteinisassociatedwithschizophreniaandisseeninavarietyofhumantumorcelllines.Also,aberrantreleaseofthisproteinisassociatedwiththeprogressionofAlzheimer"sdisease.
GeneSymbol
  • SEMA3A
  • SEMAD
  • SEMAIII
  • SEMA1-PEN
  • semaphorin-like
  • MGC133243
  • SEMA1
  • Hsema-I
  • Hsema-III
  • SemD
  • coll-1
  • SEMAL
UniProtNumber
UniProtSummaryFUNCTION:SwissProt:Q14563#Inducesthecollapseandparalysisofneuronalgrowthcones.Couldserveasaligandthatguidesspecificgrowthconesbyamotility-inhibitingmechanism.Bindstothecomplexneuropilin-1/plexin-1(Bysimilarity).
SIZE:771aminoacids;88889Da
SUBCELLULARLOCATION:Secreted(Bysimilarity).
DOMAIN:SwissProt:Q14563Strongbindingtoneuropilinismediatedbythecarboxythirdoftheprotein.
SIMILARITY:Belongstothesemaphorinfamily.&Contains1Ig-likeC2-type(immunoglobulin-like)domain.&Contains1PSIdomain.&Contains1Semadomain.
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。