
Millipore/AB9600 | Anti-Neuropilin-1 Antibody/AB9600/100 µL
市场价:
¥5960.00
美元价:
3576.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | |
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CatalogueNumber | AB9600 |
BrandFamily | Chemicon® |
TradeName |
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Description | Anti-Neuropilin-1Antibody |
ProductInformation | |
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Format | AffinityPurified |
Presentation | AffinitypurifiedimmunoglobulininPBScontaining50%glycerol,1mg/mLBSAand0.05%sodiumazide. |
StorageandShippingInformation | |
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StorageConditions | Maintainat-20°Cinundilutedaliquotsforupto6monthsafterdateofreceipt.Avoidrepeatedfreeze/thawcycles. |
BIOLOGicalInformation | |
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Immunogen | SyntheticpeptidefromtheN-terminalCUBdomainofhumanneuropilin-1. |
Host | Rabbit |
Specificity | Neuropilin-1.Theimmunogensequencehaslowhomologywithneuropilin-2. |
SpeciesReactivity |
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SpeciesReactivityNote | Itisexpectedthattheantibodywillalsoreactwithratandmouse. |
AntibodyType | PolyclonalAntibody |
EntrezGeneNumber | |
EntrezGeneSummary | NRP1isamembrane-boundcoreceptortoatyrosinekinasereceptorforbothvascularendothelialgrowthfactor(VEGF;MIM192240)andsemaphorin(seeSEMA3A;MIM603961)familymembers.NRP1playsversatilerolesinangiogenesis,axonguidance,cellsurvival,migration,andinvasion.[suppliedbyOMIM] |
GeneSymbol |
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UniProtNumber | |
UniProtSummary | FUNCTION:SwissProt:O14786#Thesolubleisoform2bindsVEGF-165andappearstoinhibititsbindingtocells.ItmayalsoinduceapoptosisbysequesteringVEGF-165.Maybindaswellvariousmembersofthesemaphorinfamily.Itsexpressionhasanaverseeffectonbloodvesselnumberandintegrity. SIZE:923aminoacids;103120Da SUBUNIT:HeterodimerwithNRP2(Probable).BindsPLXNB1. SUBCELLULARLOCATION:Cellmembrane;Single-passtypeImembraneprotein.&Isoform2:Secreted. TISSUESPECIFICITY:Theexpressionofisoforms1and2doesnotseemtooverlap.Isoform1isexpressedbythebloodvesselsofdifferenttissues.Inthedevelopingembryoitisfoundpredominantlyinthenervoussystem.Inadulttissues,itishighlyexpressedinheartandplacenta;moderatelyinlung,liver,skeletalmuscle,kidneyandpancreas;andlowinadultbrain.Isoform2isfoundinliverhepatocytes,kidneydistalandproximaltubules. SIMILARITY:SwissProt:O14786##Belongstotheneuropilinfamily.&Contains2CUBdomains.&Contains2F5/8typeCdomains.&Contains1MAMdomain. |
PhysicochemicalInformation |
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Dimensions |
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MaterialsInformation |
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MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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