密理博/AB5781 |抗斯陶芬抗体/AB5781/100µ；G
市场价：
¥6980.00
美元价：
4188.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | AB5781 |
| BrandFamily | Chemicon® |
| TradeName |
|
| Description | Anti-StaufenAntibody |
| BackgroundInformation | Staufenhomolog1bindsdouble-strandedRNA(regardlessofthesequence)andtubulin.ItmayplayaroleinspecificpositioningofmRNAsatgivensitesinthecellbycross-linkingcytoskeletalandRNAcomponents,andinstimulatingtheirtranslationatthesite. |
| ProductInformation | |
|---|---|
| Format | AffinityPurified |
| Presentation | Affinitypurifiedimmunoglobulin.LiquidinPBScontaining0.1%sodiumazide. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainat2-8°Cinundilutedforupto6monthsafterdateofreceipt.Avoidrepeatedfreeze/thawcycles. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | Syntheticpeptidefromaminoacids458-472ofhumanStaufen1. |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Rabbit |
| Specificity | ReactswithStaufen1. |
| SpeciesReactivity |
|
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | Staufenisamemberofthefamilyofdouble-strandedRNA(dsRNA)-bindingproteinsinvolvedinthetransportand/orlocalizationofmRNAstodifferentsubcellularcompartmentsand/ororganelles.TheseproteinsarecharacterizedbythepresenceofmultipledsRNA-bindingdomainswhicharerequiredtobindRNAshavingdouble-strandedsecondarystructures.ThehumanhomologueofstaufenencodedbySTAU,inadditioncontainsamicrotubule-bindingdomainsimilartothatofmicrotubule-associatedprotein1B,andbindstubulin.TheSTAUgeneproducthasbeenshowntobepresentinthecytoplasminassociationwiththeroughendoplasmicreticulum(RER),implicatingthisproteininthetransportofmRNAviathemicrotubulenetworktotheRER,thesiteoftranslation.FivetranscriptvariantsresultingfromalternativesplicingofSTAUgeneandencodingthreeisoformshavebeendescribed.Threeofthesevariantsencodethesameisoform,however,differintheir5"UTR. |
| GeneSymbol |
|
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:O95793#Bindsdouble-strandedRNA(regardlessofthesequence)andtubulin.MayplayaroleinspecificpositioningofmRNAsatgivensitesinthecellbycross-linkingcytoskeletalandRNAcomponents,andinstimulatingtheirtranslationatthesite. SIZE:577aminoacids;63182Da SUBUNIT:Bindstubulin.Bindswithlowaffinitysingle-strandedRNAorDNAhomopolymers.InteractswithCASC3inanRNA-dependentmanner(Bysimilarity).InteractswiththeinfluenzavirusnonstructuralproteinNS1. SUBCELLULARLOCATION:Roughendoplasmicreticulum.Note=Localizesexclusivelywiththeroughreticulumendoplasmic(RER). TISSUESPECIFICITY:Widelyexpressed.Expressedinbrain,pancreas,heart,skeletalmuscles,liver,lung,kidneyandplacenta. DOMAIN:SwissProt:O95793OneoftheDRDBcouldbeinvolvedinRERbinding.&TheC-terminalcontainsthetubulinbindingdomain(TBD)(Bysimilarity). SIMILARITY:Contains3DRBM(double-strandedRNA-binding)domains. |
| PhysicochemicalInformation |
|---|
| Dimensions |
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| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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